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Sunday, 05 March
13:03
Antioxidant, cytotoxic, and antibacterial activities of Clitoria ternatea flower extracts and anthocyanin-rich fraction. "IndyWatch Feed Health"
PMID: Sci Rep. 2022 Sep 1 ;12(1):14890. Epub 2022 Sep 1. PMID: 36050436 Abstract Title: Antioxidant, cytotoxic, and antibacterial activities of Clitoria ternatea flower extracts and anthocyanin-rich fraction. Abstract: Clitoria ternatea flower is a traditional medicinal herb that has been used as a natural food colourant. As there are limited studies on investigating the bioactivities of the anthocyanin-rich fraction of Clitoria ternatea flower, this study aimed to determine an efficient column chromatography method to obtain the anthocyanin-rich fraction from this flower and characterise its composition, antioxidant, antibacterial, and cytotoxic activities. Amberlite XAD-16 column chromatography was more efficient in enriching the total anthocyanin content (TAC) of the fraction with the highest TAC to total phenolic content (TPC) ratio of 1:6 than that using C18-OPN. A total of 11 ternatin anthocyanins were characterised in the anthocyanin-rich fraction by LC-MS analysis. The antioxidant activity of the anthocyanin-rich fraction was more potent in the chemical-based assay with an ICvalue of 0.860.07 mg/mL using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay than cellular antioxidant assay using RAW 264.7 macrophages. In vitro cytotoxicity assay using human embryonic kidney HEK-293 cell line showed the anthocyanin-rich fraction to be more toxic than the crude extracts. The anthocyanin-rich fraction had more potent antibacterial activity than the crude extracts against Bacillus cereus, Bacillus subtilis, and Escherichia coli. The anthocyanin-rich fraction of C. ternatea has the potential to be used and developed as a functional food ingredient or nutraceutical agent.
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Saturday, 04 March
08:19
Influence of the maternal high-intensity-interval-training on the cardiac Sirt6 and lipid profile of the adult male offspring in rats. "IndyWatch Feed Health"
PMID: PLoS One. 2020 ;15(8):e0237148. Epub 2020 Aug 3. PMID: 32745152 Abstract Title: Influence of the maternal high-intensity-interval-training on the cardiac Sirt6 and lipid profile of the adult male offspring in rats. Abstract: The susceptibility to cardiovascular disease in offspring could be reduced prior to birth through maternal intervention, before and during pregnancy. We evaluated whether the initiation periods of maternal exercise in preconception and pregnancy periods induce beneficial effects in the adult male offspring. Thirty-two female rats were divided into control and exercise groups. The exercise groups involve exercise before pregnancy or the preconception periods, exercise during pregnancy, and exercise before and during pregnancy. The mothers in the exercise groups were run on the treadmill in different periods. Then the birth weight and weekly weight gain of male offspring were measured, and the blood and left ventricle tissue of samples were collected for analysis of the Sirtuin 6 (Sirt6) and insulin growth factor-2 (IGF-2) gene expression, serum levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), cholesterol (Cho), and triglycerides (TG). There was no significant difference in the birth weight of offspring groups (P = 0.246) while maternal HIIT only during pregnancy leads to reduce weekly weight gain of offspring. Our data showed that Sirt6 and IGF-2 gene expression was increased (P = 0.017) and decreased (P = 0.047) by maternal exercise prior to and during pregnancy, respectively. Also, the serum level of LDL (p = 0.002) and Cho (P = 0.007) were significantly decreased and maternal exercise leads to improves the running speed of the adult male offspring (p = 0.0176). This study suggests that maternal HIIT prior to and during pregnancy have positive intergenerational consequence in the health and physical readiness of offspring.
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Friday, 03 March
14:47
Pelvic floor muscle massage can improve endometrial thickness and subendometrial blood flow. "IndyWatch Feed Health"
PMID: Comput Math Methods Med. 2022 ;2022:2803363. Epub 2022 Jun 29. PMID: 35813410 Abstract Title: Effects of Pelvic Floor Muscle Massage on the Pregnancy Outcome of Frozen Embryo Transfer in Patients with Thin Endometrium. Abstract: OBJECTIVE: To observe the effects of pelvic floor muscle mass on the priority outcome of frozen embryo transfer in patients with thin endometrium.METHODS: The patients who were prepared for freeze-thaw embryo transfer were randomly divided into the study group and control group. Both groups of patients began to take estradiol valerate tablets 3mg on the third day of menstrual cycle and added progesterone for luteal support after 14 days. Both groups selected high-quality embryos for embryo transfer on the day of embryo transfer. The basic information, embryo transfer, intimal thickness, intimal type, clinical pregnancy rate, and early abortion rate of the two groups were compared.RESULTS: The intimal thickness of patients in the control group and the study group on the second day of menstruation was (0.490.03) and (0.450.02) and that before progesterone was (1.170.03) and (1.200.04), respectively (
Wednesday, 01 March
11:47
10 Simple Diet Hacks For A Healthy Lifestyle Fiona Peacock BellyBelly
Many people fall into the trap of trying out diet fads, only to regain any lost weight as soon as they drop the diet. Not only is this frustrating but it can lead to you gaining more than you lost, leaving you heavier than when you started.
Yoyo dieting is bad for your health, and you should make a conscious effort to avoid it. One study from Columbia University Irving Medical Center even found a link between yoyo dieting and heart disease risk in women.
Even though you might want to believe theres a simple diet that can change your life, the reality is that long-lasting change is the way to achieve healthy weight loss.
Keep reading to discover ten simple diet hacks (or lifestyle choices) that can help you lose weight the healthy way.
#1. Set realistic long-term goals
Youre not going to lose a pound overnight; if you do, youre likely to put it on again by the end of the month. Stop setting yourself unrealistic goals and instead focus on a long-term plan.
Rather than fixating on how much weight you should lose this week, you should focus on how you want to feel in six months.
Set a long-term goal and then figure out smaller steps you can take to achieve that goal. For example, if you want to feel healthier, you can exercise regularly and improve your stamina. If you want to lose weight, you can focus on making healthy food swaps each day (e.g. switching out a packet of crisps for a snack of wholemeal pitta with hummus).
#2. Eat a hearty breakfast
Many people skip breakfast in the hope it will help them lose weight but you might be surprised to hear it can have the opposite effect.
Skipping breakfast can leave you feeling hungry and more likely to make bad food choices later in the day. The better option is to fill up on a healthy breakfast first thing in the morning.
Remember: what you eat for breakfast kickstarts your metabolism. If you begin the day with high glycemic foods, your whole day will be a sugar yoyo and no one likes a sugar crash.
Healthy breakfast ideas can include some of your favorite foods, such as avocados, meats, greek yogurt, fresh fruit and porridge (not all mixed together, obviously).
See our article on Healthy Breakfast 13 Delicious and Healthy Breakfast Ideas.
#3. Stay hydrated
Its a simple switch, but staying hydrated could improve your health. If you drink lots of juices, sodas and caffeinated drinks, try switching some for water. Drink your water with ice and lemon; you could even spice it up by adding some fruits and herbs, such as strawberries and mint for added flavo...