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Friday, 07 July
21:00
Delabeling Penicillin Allergies: A Public Service Announcement from Science-Based Medicine Science-Based Medicine
Is your child allergic to penicillin? Are you sure about that? Penicillin allergy is much less common than widely believed and there is a big push to delabel pediatric and adult patients who actually can tolerate these antibiotics.
The post Delabeling Penicillin Allergies: A Public Service Announcement from Science-Based Medicine first appeared on Science-Based Medicine.20:00
Publisher blacklists authors after preprint cites made-up studies Retraction Watch
Last month, a millipede expert in Denmark received an email notifying him that one of his publications had been mentioned in a new manuscript on Preprints.org. But when the researcher, Henrik Enghoff, downloaded the paper, he learned that it cited his work for something off-topic.
Stranger still, the authors of the now-withdrawn preprint, a group of researchers in China and Africa, also referenced two papers by Enghoff that he knew he hadnt written. It turned out they didnt exist.
Ive never had anything like this happen before, Enghoff, a professor at the Natural History Museum of Denmark, in Copenhagen, told Retraction Watch.
Flabbergasted, Enghoff reached out to David Richard Nash at the University of Copenhagen. A few months prior, Nash had been experimenting with OpenAIs ChatGPT, an artificial-intelligence chatbot, to see if it could be used to find scientific literature. He asked the bot to provide him with recent references on the butterfly species he works with. It came back with 10 plausible-looking papers, only one of which existed, Nash told Retraction Watch.
After learning of Enghoffs case, Nash emailed Preprints.org, a free preprint server owned by the scientific publisher MDPI. He explained that he had looked up five random references in the preprint and found that all of them were fictitious. He also hinted that generative artificial intelligence such as ChatGPT could have been at work, adding:
I suggest that you contact the authors directly and ask for an explanation (and hopefully a retraction and apology to the affected authors of these fake references), and also review your policies regarding accepting AI-generated textxs [sic] and references.
In correspondence shared with Retraction Watch, Lloyd Shu, prepri...
16:58
11:25
Sea cucumber hydrolysate alleviates immunosuppression and gut microbiota imbalance induced by cyclophosphamide. GreenMedInfo
PMID: Foods. 2023 Apr 10 ;12(8). Epub 2023 Apr 10. PMID: 37107399 Abstract Title: Sea Cucumber Hydrolysate Alleviates Immunosuppression and Gut Microbiota Imbalance Induced by Cyclophosphamide in Balb/c Mice through the NF-B Pathway. Abstract: This study aimed to investigate the effect of sea cucumber hydrolysate (SCH) on immunosuppressed mice induced by cyclophosphamide (Cy). Our findings demonstrated that SCH could increase the thymus index and spleen index, decrease the serum alanine transaminase (ALT) and aspartate aminotransferase (AST) levels, increase the serum IgG and small intestinal sIgA levels, reduce small intestinal and colon tissue damage, and activate the nuclear factor-B (NF-B) pathway by increasing TRAF6 and IRAK1 protein levels, as well as the phosphorylation levels of IBand p65, thereby enhancing immunity. In addition, SCH alleviated the imbalance of the gut microbiota by altering the composition of the gut microbiota in immunosuppressed mice. At the genus level, when compared with the model group, the relative abundance of,, andincreased, while that of,, anddecreased in the SCH groups. Moreover, 26 potential bioactive peptides were identified by oligopeptide sequencing and bioactivity prediction. This study's findings thus provide an experimental basis for further development of SCH as a nutritional supplement to alleviate immunosuppression induced by Cy as well as provides a new idea for alleviating intestinal damage induced by Cy.
10:42
Sea cucumber phospholipids could ameliorate the atherosclerosis symptoms by regulating cholesterol metabolism. GreenMedInfo
PMID: J Nutr. 2023 Jun ;153(6):1762-1770. Epub 2023 Apr 25. PMID: 37105382 Abstract Title: Sea Cucumber Phospholipids Regulate Cholesterol Metabolism in High-Fat Diet-Induced ApoEMice. Abstract: BACKGROUND: Sea cucumber phospholipids, marine-derived lipids with high nutritional functions, have been proven to exhibit various biological activities. However, it is unclear how sea cucumber phospholipids regulate cholesterol (Chol) metabolism in atherosclerosis.OBJECTIVES: This study aimed to investigate the effects and mechanism of sea cucumber phospholipids on the metabolism of Chol and cholesterol esters (CE) in ApoEmice, including plasmenyl phosphatidylethanolamine (PE-P) and plasmanyl phosphatidylcholine (PC-O).METHODS: Male ApoEmice were fed with Chow diet, high-fat diet (HFD), and HFD supplemented with PC-O or PE-P, respectively. We integrated a targeted lipidomics strategy to classify and compare the cholesteryl esters according to their fatty acid types, and then analyzed the individual cholesteryl ester molecular species in the liver and serum of mice. Furthermore, the Chol metabolism-related genes and pathways were analyzed in high-fat-induced ApoEmice.RESULTS: Biochemical analysis showed that sea cucumber phospholipids significantly inhibit the generation of arterial plaque in ApoEmice. Compared with the HFD group, PE-P significantly reduced the contents of SFA-CE and MUFA-CE in mice liver (P
10:35
Sea cucumber sulfated polysaccharides and Lactobacillus gasseri synergistically ameliorate the overweight induced by altered gut microbiota. GreenMedInfo
PMID: Food Funct. 2023 May 11 ;14(9):4106-4116. Epub 2023 May 11. PMID: 37039235 Abstract Title: Sea cucumber sulfated polysaccharides andsynergistically ameliorate the overweight induced by altered gut microbiota in mice. Abstract: Sulfated polysaccharides from sea cucumber(SCSPsj) have been found to modulate the gut microbiota by promoting the growth of probiotics. However, the effects of the combination of SCSPsj and probiotics are still less known. Thus, the present study aimed to investigate the effects of SCSPsj andon gut microbiota-altered mice through gut microbiota and metabolomics analysis. In the present study, supplementation with SCSPsj,or the combination of SCSPsj andcould effectively ameliorate the body weight gain and fat accumulation in gut microbiota-altered mice treated with low-dose penicillin. The better effect of the combination of SCSPsj andis attributed to the synergistic effect of SCSPsj and. 16S rRNA sequencing revealed that the combination of SCSPsj andcan synergistically improve gut microbiota dysbiosis by increasingand reducing. Furthermore, metabolomics results revealed that the combination of SCSPsj andcan alleviate metabolic disorders by reducing the levels of lipid and lipid-like molecules in the serum samples, such as-vaccenic acid and 3-hydroxy-5-cholestene. Our findings have proved that the combination of SCSPsj andcan benefit host health attributed to the synergistic effect, which is conducive to further application in functional food.
10:31
Combination of vitamin D and probiotics inhibits chemically induced colorectal carcinogenesis. GreenMedInfo
PMID: Life Sci. 2023 Jun 1 ;322:121617. Epub 2023 Mar 30. PMID: 37003542 Abstract Title: Combination of vitamin D and probiotics inhibits chemically induced colorectal carcinogenesis in Wistar rats. Abstract: UNLABELLED: The modulation of inflammatory elements, cell differentiation and proliferation by vitamin D and the role of probiotics in the intestinal microbiota and immunogenic response have sparked interest in the application of both in chemotherapeutics and chemoprevention of colorectal tumors.AIMS: The present study aimed to investigate the effects of isolated and/or combined treatment of vitamin D3 and probiotics on colorectal carcinogenesis.MAIN METHODS: Pre-neoplastic lesions were induced with 1,2-dimethylhydrazine in the colon of Wistar rats, which were treated with probiotics and/or vitamin D in three different approaches (simultaneous, pre-, and post-treatment). We investigated the frequency of aberrant crypt foci (ACF) and aberrant crypt (AC) in the distal colon, fecal microbiome composition, gene and protein expression through immunohistochemical and RT-PCR assays, and general toxicity through water consumption and weight gain monitoring.KEY FINDINGS: Results confirm the systemic safety of treatments, and show a protective effect of vitamin D and probiotics in all approaches studied, as well as in combined treatments, with predominance of different bacterial phyla compared to controls. Treated groups show different levels of Nrf2, GST, COX2, iNOS,-catenin and PCNA expression.SIGNIFICANCE: These experimental conditions explore the combination of vitamin D and probiotics supplementation at low doses over pathways involved in distinct stages of colorectal carcinogenesis, with results supporting its application in prevention and long-term strategies.
10:30
Lactobacillus gasseri LG-G12 restores gut microbiota and intestinal health in obesity mice on ceftriaxone therapy. GreenMedInfo
PMID: Foods. 2023 Mar 3 ;12(5). Epub 2023 Mar 3. PMID: 36900609 Abstract Title: LG-G12 Restores Gut Microbiota and Intestinal Health in Obesity Mice on Ceftriaxone Therapy. Abstract: Gut microbiota imbalance is associated with the occurrence of metabolic diseases such as obesity. Thus, its modulation is a promising strategy to restore gut microbiota and improve intestinal health in the obese. This paper examines the role of probiotics, antimicrobials, and diet in modulating gut microbiota and improving intestinal health. Accordingly, obesity was induced in C57BL/6J mice, after which they were redistributed and fed with an obesogenic diet (intervention A) or standard AIN-93 diet (intervention B). Concomitantly, all the groups underwent a treatment phase withLG-G12, ceftriaxone, or ceftriaxone followed byLG-G12. At the end of the experimental period, the following analysis was conducted: metataxonomic analysis, functional profiling of gut microbiota, intestinal permeability, and caecal concentration of short-chain fatty acids. High-fat diet impaired bacterial diversity/richness, which was counteracted in association withLG-G12 and the AIN-93 diet. Additionally, SCFA-producing bacteria were negatively correlated with high intestinal permeability parameters, which was further confirmed via functional profile prediction of the gut microbiota. A novel perspective on anti-obesity probiotics is presented by these findings based on the improvement of intestinal health irrespective of undergoing antimicrobial therapy or not.
10:24
Lactobacillus gasseri NK109 and its supplement alleviate cognitive impairment. GreenMedInfo
PMID: Nutrients. 2023 Feb 3 ;15(3). Epub 2023 Feb 3. PMID: 36771498 Abstract Title: NK109 and Its Supplement Alleviate Cognitive Impairment in Mice by Modulating NF-B Activation, BDNF Expression, and Gut Microbiota Composition. Abstract: Aging-related gut microbiota dysbiosis initiates gut inflammation and microbiota dysbiosis, which induce the occurrence of psychiatric disorders including dementia. The alleviation of gut microbiota dysbiosis by probiotics is suggested to be able to alleviate psychiatric disorders including cognitive impairment (CI). Therefore, to understand how probiotics could alleviate CI, we examined the effects of anti-inflammatoryNK109 and its supplement (NS, mixture of NK109 and soybean embryo ethanol extract) on cognitive function in aged (Ag), 5XFAD transgenic (Tg), or mildly cognition-impaired adult fecal microbiota (MCF)-transplanted mice. Oral administration of NK109 or NS decreased CI-like behaviors in Ag mice. Their treatments suppressed TNF-and p16 expression and NF-B-activated cell populations in the hippocampus and colon, while BDNF expression was induced. Moreover, they partially shifted the-diversity of gut microbiota in Ag mice to those of young mice: they decreased Bifidobacteriaceae, Lactobacillaceae, and Helicobacteriaceae populations and increased Rikenellaceae and Prevotellaceae populations. Oral administration of NK109 or NS also reduced CI-like behaviors in Tg mice. Their treatments induced BDNF expression in the hippocampus, decreased hippocampal TNF-and Aexpression and hippocampal and colonic NF-B-activated cell populations. NK109 and NS partially shifted the-diversity of gut microbiota in Tg mice: they decreased Muribaculaceae and Rhodospiraceae populations and increased Helicobacteriaceae population. Oral administration of NK109 or NS decreased MCF transplantation-induced CI-like behaviors in mice. NK109 and NS increased hippocampal BDNF expression, while hippocampal and colonic TNF-expression and NF-B-activated cell populations decreased. These findings suggest that dementia can fluctuate the gut microbiota composition and NK109 and its supplement NS can alleviate CI with systemic inflammation by inducing BDNF expression and suppressing NF-B activation and gut microbiota dysbiosis.
10:16
Protective effects of Lactobacillus gasseri against high-cholesterol diet-induced fatty liver. GreenMedInfo
PMID: Int J Mol Sci. 2023 Jan 20 ;24(3). Epub 2023 Jan 20. PMID: 36768377 Abstract Title: Protective Effects ofagainst High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles. Abstract: Fatty liver is one of the most pervasive liver diseases worldwide. Probiotics play an important role in the progression of liver disease, but their effects on host regulation are poorly understood. This study investigated the protective effects of lactobacillus gasseri () against high-cholesterol diet (HCD)-induced fatty liver injury using a zebrafish larvae model. Liver pathology, lipid accumulation, oxidative stress and hepatic inflammation were evaluated to demonstrate the changes in a spectrum of hepatic injury. Moreover, multiple indexes on host gene expression profiles were comprehensively characterized by RNA screening. The results showed that treatment withameliorated HCD-induced morphological and histological alterations, lipid regulations, oxidative stress and macrophage aggregation in the liver of zebrafish larvae. Furthermore, the enrichment of the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway revealed that the core pathways ofregulation were interleukin-17 (IL-17) signaling, phosphoinositide 3-kinase (PI3K)-AKT signaling pathway, the regulation of lipolysis and adipocytes and fatty acid elongation and estrogen signaling. The genes at key junction nodes, hsp90aa1.1, kyat3, hsd17b7, irs2a, myl9b, ptgs2b, cdk21 and papss2a were significantly regulated byadministration. To conclude, the current research extends our understanding of the protective effects ofagainst fatty liver and provides potential therapeutic options for fatty liver treatment.
10:00
Kennedys Health Policy Roundtable Articles
June 27, 2023, Robert F. Kennedy Jr. held a Health Policy Roundtable featuring a panel of health freedom advocates, including yours truly; my good friend Dr. Patrick Gentempo; Maureen McDonnell, a holistic pediatric nurse; Dr. Pierre Kory, cofounder of the Frontline COVID Critical Care Alliance (FLCCC); filmmaker Mikki Willis; Sayer Ji, founder of Greenmed.com; and Dr. Sherri Tenpenny.
Opening Statements
The event was hosted by Mary Holland, former president and general counsel for Childrens Health Defense (CHD), an organization founded by Kennedy. Shes currently on a leave of absence from the CHD to work on Kennedys presidential campaign.
I'm on the campaign in large part because of Mr. Kennedy's strong stance to protect freedom, including health freedom, and to protect fundamental human rights, Holland said in her opening statement.
Many of you watching are key supporters of the health freedom movement, and you're familiar with a lot of the things Mr. Kennedy has been talking about over the years about agency capture, corporate greed, corruption, pharmaceutical and medical harm, and abuse of government power, especially during COVID ... and most of you agree that the U.S. healthcare system needs deep reform, which is our subject tonight.
Charles Eisenstein, who has been working closely with Kennedy on policy and messaging moderated the event.
What distinguishes the people on this panel is courage, Eisenstein said. This is not merely an abstract ideal health freedom for any of us here. It's something that all of us have risked our careers for ...
What unifies us is a certain independence of thought, and also a practicality that we're actually seeking to do something about it, at a time when the information landscape has become so fragmented that it's hard to tell who to trust and what to believe, when the traditional authorities have lost the trust of the public.
I hope that everybody listening will tune in both to the content of what is said [and] to the tone of the inquiry, and to trust your instincts on who is sincere and who is truthful. Run it by your reason and logic ...
Many of us have been alternative for a very long time. This is the moment where the collapsing center ... the dysfunctional health system, finally opens up, and what has so long been alternative might become a new mainstream that could transform the health of this country. This is the ... possibility that we're engaged in.
As expected, mainstream media have had nothing good to say about the event, attempting to smear Ken...
Why $4.99 Costco Chicken Is a Massive Problem Articles
Editor's Note: This article is a reprint. It was originally published October 29, 2019.
If you live in the U.S. and frequent Costco, you're probably familiar with their $4.99 rotisserie chicken. It's one of the standard items Costco sells that pull in repeat customers. As reported by CNN:1
"The chickens have become almost a cult item. 91 million were sold last year, double the number from a decade earlier. They have their own Facebook page with nearly 13,000 followers. So Costco is willing to go to extreme lengths to keep its chickens at $4.99."
However, as with all foods raised in concentrated animal feeding operations (CAFOs), this cheap fare comes with steep, hidden costs. CAFOs are a primary contributor to several problems, including environmental pollution and antibiotic-resistant disease.
The fact that Costco is willing to go to great lengths to keep the price of its chicken at rock bottom means the problems associated with its CAFOs are likely to only get worse. As reported by CNN in 2019,2 Costco was planning on opening its very own poultry complex in Fremont, Nebraska, which will allow it to "control the production process from farm to store."
One of the stated reasons for Costco's decision to invest in its own poultry operation is because they're having trouble procuring the right size broilers. Rotisserie chickens need to be right around 6 pounds, and many CAFO chickens today can go as high as 7 or 8 pounds,3 which are too large for the rotisserie.
Chicken Farming Isn't What It Used To Be
Critics have rightfully pointed out that Costco's move to open a 400,000 square-foot chicken CAFO in Nebraska will have negative repercussions for the environment. When interviewed by CNN, Randy Ruppert, a Fremont environmental activist, pointed out the facility will produce toxic runoff such as ammonia and nitrates.
He rightfully refers to it as "degenerative farming," which it is. CNN also highlights the unfair contract agreements involved. A vast majority of American chicken farmers work under a contract system that shifts the financial risks to the farmers while providing them with few benefits.
Contract farmers are responsible for building and maintaining the barns, while the companies supply the chicks and feed and set all the rules. As noted by Robert Taylor, Professor Emeritus of agricultural economics at Auburn University, this type of contract "essentially makes the farmer an indentured servant" or "chicken house janitor."...
Damaged People, Rotten Standards: Anatomy of Decline Articles
Defining the Problem
The "new normal" has snuck up on us. No, there are no big screens broadcasting the babble of Klaus Schwab, dressed up as Ze Big Bro. There is no CBDC for the peasants and no climate lockdowns not yet. But the "new normal" is here because the people have been eaten into. You can see it in their faces.
Many of the less resilient ones have checked out. The so called "new normal" is, in fact, a lack of any kind of a rational or honorable baseline in people's heads. There are no standards, no accountability, just a Kafkaesque free fall, wrapped in politically correct words.
After a very long time of physical poisoning, soul stomping, social decline, and erosion of standards followed by three years of deliberate torment many people have just shut down. Gone inside. Brought their baseline to a very low level so as to feel "normal" in a world that is anything but.
On my end, I've been noticing signs of decline and Soviet-like absurdity in the U.S. ever since 2001. But before 2020 it was subtler: TSA (okay, maybe not so subtle when it comes to the TSA), a rude customer service representative here and there, dirty public bathrooms, paranoia-installing announcements on the train to "see something, say something," and so on. But today, the "glitter curtain" is off, and the subtlety is all but gone!
Social engineering takes time. It takes at least a full generation to create a solid shift toward a new psychological mode. And that is what happened. Today, the people who were born after 2001 are no longer kids but young adults. The aspirating masters have been working on shifting people's values from "proud consumer individualism" to "fear-driven subservience" for at least two decades and the result of their trickery is here.
Not Being Able to Work
In addition to the psychological shift, there is also a visible shift in people's ability to work:
"I see it everywhere. The standards are in the toilet. Nobody has the energy to care. The delivery people don't look you in the eye, they just throw the stuff on the floor and hurry off. Younger cashiers also often don't look you in the eye and don't respond to greetings. Packages get destroyed, stolen, and lost. Tracking doesn't work. Censorship algorithms are a black box that you can't argue with.
Asking people to think is perceived as an arrogant insult or a personal attack. Thinking is, in fact, "snotty." And have you seen those "stay away" damaged teens on the train with empty, mentally challenged eyes? They have been damaged perhaps irreparably, they are not there. Can't reach. So many people you just can't reach.
They don't feel well and they can't think. Asking them to act alive is asking them for too much. It is pu...
09:51
Healthy Traditions Expands Local Network Distribution New Online Payment Options Bypassing Credit Cards Medical Kidnap
Press Release
HealthyTraditions.com
In anticipation of a U.S. financial collapse and restructuring of the U.S. Banking system, Healthy Traditions has increased its local distribution network, and added new payment options that bypass credit cards.
Brian Shilhavy, the Founder and CEO of Healthy Traditions has stated:
If U.S. regulatory requirements for conducting business online start requiring online consumers and businesses to comply with National ID standards that link customer accounts to federal digital currencies such as Central Bank Digital Currencies, or Digital IDs that include biometrics, in order to participate in online ecommerce, we will cease doing business on the Internet and only distribute our products through local distributors.
The Naturally A Deal Co-op has been added to the list of Healthy Traditions distributors, with local distribution covering the Southeast, mid-Atlantic states, as well as Ohio and Michigan. (Source.)
About the Co-op
Naturally a Deal specializes in closeout food, especially natural foods, at prices far below retail level, and they carry a nice selection of bulk foods and fresh, seasonal produce.
Due to the co-op nature of their business, its very important to only order during the set ordering period and pickup at the pre-scheduled pickup time. The deliveries are typically every 3-6 weeks, based on order size; though, theres no minimal amount or frequency you need to order.
If youre interested in signing up, go to NaturallyADeal.com. Please help spread the word so that we can get a large enough group together for them to start delivering!
How the Co-op Works
Sign up under the right location on our website to view items. Theres no commitment associated with creating a free account.
Ordering is every 3 or 6 weeks depending on how large the group order is.
–...
09:50
Healthy Traditions Expands Local Network Distribution New Online Payment Options Bypassing Credit Cards Vaccine Impact
Press Release
HealthyTraditions.com
In anticipation of a U.S. financial collapse and restructuring of the U.S. Banking system, Healthy Traditions has increased its local distribution network, and added new payment options that bypass credit cards.
Brian Shilhavy, the Founder and CEO of Healthy Traditions has stated:
If U.S. regulatory requirements for conducting business online start requiring online consumers and businesses to comply with National ID standards that link customer accounts to federal digital currencies such as Central Bank Digital Currencies, or Digital IDs that include biometrics, in order to participate in online ecommerce, we will cease doing business on the Internet and only distribute our products through local distributors.
The Naturally A Deal Co-op has been added to the list of Healthy Traditions distributors, with local distribution covering the Southeast, mid-Atlantic states, as well as Ohio and Michigan. (Source.)
About the Co-op
Naturally a Deal specializes in closeout food, especially natural foods, at prices far below retail level, and they carry a nice selection of bulk foods and fresh, seasonal produce.
Due to the co-op nature of their business, its very important to only order during the set ordering period and pickup at the pre-scheduled pickup time. The deliveries are typically every 3-6 weeks, based on order size; though, theres no minimal amount or frequency you need to order.
If youre interested in signing up, go to NaturallyADeal.com. Please help spread the word so that we can get a large enough group together for them to start delivering!
How the Co-op Works
Sign up under the right location on our website to view items. Theres no commitment associated with creating a free account.
Ordering is every 3 or 6 weeks depending on how large the group order is.
–...
09:36
Lactobacillus gasseri LA806 supplementation in patients with irritable bowel syndrome. GreenMedInfo
PMID: J Clin Med. 2022 Dec 15 ;11(24). Epub 2022 Dec 15. PMID: 36556059 Abstract Title: LA806 Supplementation in Patients with Irritable Bowel Syndrome: A Multicenter Study. Abstract: The potential benefits of Lactobacillus gasseri LA806 in IBS were previously identified in a comprehensive preclinical research program. The purpose of this multicenter study was to explore in real-life conditions changes in IBS symptoms and quality of life in patients receiving a 4-week supplementation with L. gasseri LA806. Altogether 119 patients meeting Rome IV criteria for IBS were included, of whom 118 received the supplement. The majority of patients (71.8% (95% CI 63.679.9%)) manifested a30% decrease in abdominal pain at 4 weeks, the mean abdominal pain score diminishing by 54.2% (from 5.32.2 to 2.22.4, p
09:29
Lactobacilli downregulate transcription factors in Helicobacter pylori that affect motility, acid tolerance and antimicrobial peptide survival. GreenMedInfo
PMID: Int J Mol Sci. 2022 Dec 7 ;23(24). Epub 2022 Dec 7. PMID: 36555092 Abstract Title: Lactobacilli Downregulate Transcription Factors inThat Affect Motility, Acid Tolerance and Antimicrobial Peptide Survival. Abstract: infection triggers inflammation that may lead to gastritis, stomach ulcers and cancer. Probiotic bacteria, such as, have been of interest as treatment options, however, little is known about the molecular mechanisms of-mediated inhibition ofpathogenesis. In this work, we investigated the effect ofculture supernatants, so-called conditioned medium (CM), from two gastric isolates,and, on the expression of transcriptional regulators in. Among the four known two-component systems (TCSs), i.e., ArsRS, FlgRS, CheAY and CrdRS, the flagellar regulator geneand the acid resistance associatedgene were down-regulated byCM, whereas expression of the other TCS-genes remained unaffected.CM also reduced the motility of, which is in line with reducedexpression. Furthermore, among six transcription factors ofonly the ferric uptake regulator genewas regulated byCM. Deletion offurther led to dramatically increased sensitivity to the antimicrobial peptide LL-37. Taken together, the results highlight that released/secreted factors of some lactobacilli, but not all, downregulate transcriptional regulators involved in motility, acid tolerance and LL-37 sensitivity of.
09:25
Healthy Traditions Expands Local Network Distribution New Online Payment Options Bypassing Credit Cards Health Impact News
Press Release
HealthyTraditions.com
In anticipation of a U.S. financial collapse and restructuring of the U.S. Banking system, Healthy Traditions has increased its local distribution network, and added new payment options that bypass credit cards.
Brian Shilhavy, the Founder and CEO of Healthy Traditions has stated:
If U.S. regulatory requirements for conducting business online start requiring online consumers and businesses to comply with National ID standards that link customer accounts to federal digital currencies such as Central Bank Digital Currencies, or Digital IDs that include biometrics, in order to participate in online ecommerce, we will cease doing business on the Internet and only distribute our products through local distributors.
The Naturally A Deal Co-op has been added to the list of Healthy Traditions distributors, with local distribution covering the Southeast, mid-Atlantic states, as well as Ohio and Michigan. (Source.)
About the Co-op
Naturally a Deal specializes in closeout food, especially natural foods, at prices far below retail level, and they carry a nice selection of bulk foods and fresh, seasonal produce.
Due to the co-op nature of their business, its very important to only order during the set ordering period and pickup at the pre-scheduled pickup time. The deliveries are typically every 3-6 weeks, based on order size; though, theres no minimal amount or frequency you need to order.
If you̵...
09:18
Lactobacillus gasseri RW2014 ameliorates hyperlipidemia. GreenMedInfo
PMID: Nutrients. 2022 Nov 22 ;14(23). Epub 2022 Nov 22. PMID: 36500975 Abstract Title: RW2014 Ameliorates Hyperlipidemia by Modulating Bile Acid Metabolism and Gut Microbiota Composition in Rats. Abstract: Hyperlipidemia is a leading risk of cardiovascular and cerebrovascular disease. Dietary supplementation with probiotics has been suggested as an alternative intervention to lower cholesterol. In the current study, we isolated a strain ofRW2014 (LGA) from the feces of a healthy infant fed with breast milk, and it displayed bile salt hydrolase (BSH) activity. Using this strain we determined its cholesterol-lowering and fatty liver-improving functions. SD rats were randomly divided into four groups. The control rats were fed a commercial chow diet and the other three groups were fed a high-fat diet (HFD) for a 7-week experiment period. After two weeks of feeding, the rats in PBS, simvastin, and LGA group were daily administered through oral gavage with 2 mL PBS, simvastin (1 mg/mL), and 210CFU/mouse live LGA in PBS, respectively. After five weeks of such treatment, the rats were euthanized and tissue samples were collected. Blood lipid and inflammatory factors were measured by ELISA, gut microbiota was determined by 16S rRNA sequencing, and bile acids profiles were detected by metabolomics. We found that LGA group had lower levels of blood cholesterol and liver steatosis compared to the simvastin group. LGA also significantly reducedthe levels of inflammatory factors in the serum, including TNF, IL-1, MCP-1, IL-6, and exotoxin (ET), and increased the levels of short-chain fatty acids in feces, including isobutyric acid, butyric acid, isovaleric acid, valeric acid, and hexanoic acid. In addition, LGA altered the compositions of gut microbiota as manifested by the increased ratio of Firmicutes/Bacteroides and the relative abundance ofgenus. Targeted metabolomics results showed that bile acids, especially free bile acids and secondary bile acids in feces, were increased in LGA rats compared with the control rats. Accordingly, the rats administrated with LGA also had a higher abundance of serum bile acids, including 23-norcholic acid, 7-ketolithocholic acid,-muricholic acid, cholic acid, and deoxycholic acid. Together, this study suggests that LGA may exert a cholesterol-lowering effect by modulating the metabolism of bile acids and the composition of gut microbiota.
09:01
08:59
Cisplatin conjugation with an exopolysaccharide extracted from Lactobacillus gasseri potentiates its efficacy and attenuates its toxicity. GreenMedInfo
PMID: Int J Biol Macromol. 2023 Jan 15 ;225:227-240. Epub 2022 Oct 30. PMID: 36354077 Abstract Title: Cisplatin conjugation with an exopolysaccharide extracted from Lactobacillus gasseri potentiates its efficacy and attenuates its toxicity. Abstract: The development of newer cisplatin analogs is constantly being investigated owing to its low solubility, poor pharmacokinetics, and dose-related toxicity. In order to address the limitations of current cisplatin therapy, the present study was undertaken. Cisplatin conjugation with an exopolysaccharide extracted from Lactobacillus gasseri (LG-EPS) showed remarkably enhanced and selective anticancer activity by targeting tumor cells overexpressing glucose transporter 1 (GLUT1). The EPS-cisplatin complex exhibited a 600-fold increase in aqueous solubility with a better pharmacokinetic profile (longer half-life) in comparison to cisplatin. Cell viability assay and western blotting demonstrated a strong correlation between the cytotoxicity profile and GLUT1 expressions in different cell lines. The concentration of DNA-bound platinum was also found to be significantly higher in EPS-cisplatin-treated cells. Quercetin, a competitive inhibitor of GLUTs, was shown to prevent this selective uptake of EPS-cisplatin complex. Surprisingly, EPS-cisplatin complex showed an exceptionally safer profile (4 times the maximum tolerated dose of cisplatin) in the acute toxicity study and was also more efficacious against the xenograft mice model. The study suggests that this green glycoconjugation can be an effective and safer strategy to broaden the therapeutic potential of anti-cancer drugs in general and cisplatin in particular.
08:49
Antioxidant and anti-inflammatory activity of sea cucumber active compounds. GreenMedInfo
PMID: Bioinform Biol Insights. 2023 ;17:11779322221149613. Epub 2023 Jan 16. PMID: 36688185 Abstract Title: Antioxidant and Anti-inflammatory Activity of Sea Cucumber (Active Compounds against KEAP1 and iNOS Protein. Abstract: Oxidative stress and inflammation have a role in the development of various diseases. Oxidative stress and inflammation are associated with many proteins, including Kelch ECH associating protein 1 (KEAP1) and inducible nitric oxide synthase (iNOS) proteins. The active compounds contained inhave antioxidant and anti-inflammatory properties. This study aimed to evaluate the antioxidant and anti-inflammatory activity of sea cucumber's active compounds by targeting KEAP1 and iNOS proteins. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and nitric oxide (NO) scavenging activity ofextract were measured spectrophotometrically. The 3-dimensional (3D) structures of sea cucumber's active compounds and proteins were obtained from the PubChem and Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) databases. Molecular docking was performed using AutoDock Vina software. Molecular dynamics simulations were carried out using Yet Another Scientific Artificial Reality Application (YASARA) software with environmental parameters according to the cell's physiological conditions. The membrane permeability test was performed using the PerMM web server. The methanol extract ofhad a weak antioxidant activity against DPPH and strong activity against NO radical. Scabraside and holothurinoside G had the most negative binding affinity values when interacting with the active site of KEAP1 and iNOS proteins. Molecular dynamics simulations also showed that both compounds were stable when interacting with KEAP1 and iNOS. However, scabraside and holothurinoside G were difficult to penetrate the cell plasma membrane, which is seen from the high energy transfer value in the lipid acyl chain region of phospholipids. Scabraside and holothurinoside G are predicted to act as antioxidants and anti-inflammations, but in their implementation toandstudy, it is necessary to have liposomes or nanoparticles, or other delivery methods to help these 2 compounds enter the cell.
08:00
Happy Hour Spirit of the Antichrist series with JB Hixson Dr. Tenpenny
07-06-2023 Listen to audio here. If you prefer to watch rather than listen, click on the video below: https://drtenpenny.b-cdn.net/2023/07-06-23-HHr-JBHixson-Pt1.mp4 Spirit of the Antichrist: The Gathering Cloud of Deception This []
07:43
Sea cucumber derived triterpenoid glycoside frondoside A. GreenMedInfo
PMID: Nutrients. 2023 Jan 11 ;15(2). Epub 2023 Jan 11. PMID: 36678249 Abstract Title: Sea Cucumber Derived Triterpenoid Glycoside Frondoside A: A Potential Anti-Bladder Cancer Drug. Abstract: Bladder cancer is a highly recurrent disease and a common cause of cancer-related deaths worldwide. Despite recent developments in diagnosis and therapy, the clinical outcome of bladder cancer remains poor; therefore, novel anti-bladder cancer drugs are urgently needed. Natural bioactive substances extracted from marine organisms such as sea cucumbers, scallops, and sea urchins are believed to have anti-cancer activity with high effectiveness and less toxicity. Frondoside A is a triterpenoid glycoside isolated from sea cucumber,. It has been demonstrated that Frondoside A exhibits anti-proliferative, anti-invasive, anti-angiogenic, anti-cancer, and potent immunomodulatory effects. In addition, CpG oligodeoxynucleotide (CpG-ODN) has also been shown to have potent anti-cancer effects in various tumors models, such as liver cancer, breast cancer, and bladder cancer. However, very few studies have investigated the effectiveness of Frondoside A against bladder cancer alone or in combination with CpG-ODN. In this study, we first investigated the individual effects of both Frondoside A and CpG-ODN and subsequently studied their combined effects on human bladder cancer cell viability, migration, apoptosis, and cell cycle in vitro, and on tumor growth in nude mice using human bladder cancer cell line UM-UC-3. To interrogate possible synergistic effects, combinations of different concentrations of the two drugs were used. Our data showed that Frondoside A decreased the viability of bladder cancer cells UM-UC-3 in a concentration-dependent manner, and its inhibitory effect on cell viability (2.5M) was superior to EPI (10M). We also showed that Frondoside A inhibited UM-UC-3 cell migration, affected the distribution of cell cycle and induced cell apoptosis in concentration-dependent manners, which effectively increased the sub-G1 (apoptotic) cell fraction. In addition, we also demonstrated that immunomodulator CpG-ODN could synergistically potentiate the inhibitory effects of Frondoside A on the proliferation and migration of human bladder cancer cell line UM-UC-3. In in vivo experiments, Frondoside A (800g/kg/day i.p. for 14 days) alone and in combination with CpG-ODN (1 mg/kg/dose i.p.) significantly decreased the growth of UM-UC-3 tumor xenografts, without any significant toxic side-effects; however, the chemotherapeutic agent EPI caused weight loss in nude mice. Taken together, these findings indicated that Frondoside A in combination with CpG-ODN is a promising therapeutic strategy for bladder cancer.
...
07:30
Antidepressants Can Cause Chemical Castration Mad In America
From Maryanne Demasi Reports: Antidepressants can cause severe, sometimes irreversible, sexual dysfunction that persists even after discontinuing the medication. Sufferers have described it as chemical castration a type of genital mutilation caused by antidepressants, mainly selective serotonin reuptake inhibitors (SSRIs). The condition is known as post-SSRI sexual dysfunction (PSSD), a condition largely unrecognised, and the true incidence of which is unknown.
David Healy, psychiatrist and founder of RxISK.org said, I saw my first patient with PSSD in 2000, a 35-year-old lady who told me that three months after stopping treatment, she could rub a hard-bristled brush across her genitals and feel nothing. Josef Witt-Doerring, psychiatrist and former FDA medical officer said, This condition is so devastating that it will cause serious changes to your life and to those around you.
In 2020, during protracted Covid lockdowns in Melbourne, 23-year-old Rosie Tilli felt an increasing sense of anxiety and depression. Her psychiatrist prescribed a low dose of Lexapro (escitalopram), an SSRI to help Rosie calm down, assuring her that if she experienced side effects, theyd go away once she stopped the medication. Soon after taking the medication Rosie felt emotionally blunted, but took it as a positive sign. At first, I thought it was great because it felt like the medication was working. But then I couldnt feel my emotions, I couldnt cry, I had no sexual desire, and my genitals went numb.
After four months, Rosie decided to slowly wean herself off the medication. Some of her symptoms improved and the fog lifted, but over the next two years her libido faded to nothing. It has been two years of hell. Now, I have no sexual function. Im numb down there. I cant have an orgasm. It feels like my soul has just been vacuumed out of my body. I feel completely asexual, said Rosie. She sought help from various professionals, but none believed it could be the antidepressant because the drug had already left her system. They concluded it was all in her mind.
Rosie went to a local youth centre for help, but they ended up sectioning her under the Mental Health Act with an Involuntary Treatment Order, insisting she take antipsychotic medication. I refused to take an antipsychotic because I knew I wasnt psychotic. Instead, they forced me to take another antidepressant against my will in order to leave the facility, said Rosie. It was the most traumatic thing Ive ever been through in my life. I fel...
06:58
The synergistic effect of sea cucumber saponins and caffeine on preventing obesity. GreenMedInfo
PMID: J Sci Food Agric. 2023 Jun ;103(8):3950-3960. Epub 2022 Nov 29. PMID: 36377349 Abstract Title: The synergistic effect of sea cucumber saponins and caffeine on preventing obesity in high-fat diet-fed mice by extending the action duration of caffeine. Abstract: BACKGROUND: Sea cucumber saponins (SCSs) exhibit a unique structure and high bioactivities and might have specialized implications on caffeine metabolic process by altering the activity of N-demethylation enzyme CYP1A2. The present study aimed to clarify the effects of SCS on caffeine metabolism in vivo and in vitro, as well as the synergistic anti-obesity effect of SCS and caffeine on high-fat diet-induced obese mice.RESULTS: Results found that SCS administration significantly postponed the elimination rate of caffeine and its metabolites in vivo, and further study found CYP1A2-mediated caffeine metabolism was remarkably inhibited in a dose-dependent manner in vitro. The synergistic effect of the SCS and caffeine combination could decrease the total weight of white adipose tissue by 52% compared with high-fat diet-treated group.CONCLUSION: SCS could prolong caffeine action time, and the combination of the two substances exhibited joint action on high-fat diet-induced obese mice. These findings might provide a basis for the development of functional foods and potential application using the combination of SCS and caffeine.2022 Society of Chemical Industry.
06:03
Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells. GreenMedInfo
PMID: Kaohsiung J Med Sci. 2023 Jun ;39(6):605-615. Epub 2023 Mar 24. PMID: 36960852 Abstract Title: Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells via lipid metabolism regulation at least partly by suppressing the Akt/mTOR/SREBP1 pathway. Abstract: Chemotherapy is one of the common treatment methods for breast cancer, but chemoresistance is a severe challenge. Caffeic acid phenethyl ester (CAPE) is an active ingredient of propolis extract and has been shown to have a variety of beneficial effects, and its potential as a treatment for breast cancer is worth exploring. The effects of CAPE on doxorubicin (DOX) resistance were determined by cell counting kit-8 (CCK-8) assay, colony-formation assay, and flow cytometry. Oil Red O staining and the detection of free fatty acids, triglycerides, phospholipids, and cholesterol were performed to assess the status of lipid metabolism. Quantitative polymerase chain reaction (qPCR) and western blotting were applied to investigate the molecules involved in lipid metabolism and the protein kinase B (Akt)/mammalian target of rapamycin (mTOR)/sterol regulatory element binding protein 1 (SREBP1) pathway. CAPE treatment reversed DOX resistance in breast cancer cells and suppressed their lipid metabolism. In addition, CAPE combined with DOX remarkably suppressed SREBP1 expression in part by inhibiting Akt/mTOR pathway activation. Furthermore, by inhibiting lipid metabolism, partly via the Akt/mTOR/SREBP1 pathway, CAPE ultimately reversed DOX resistance in breast cancer. Our results suggest that CAPE treatment reversed DOX resistance in breast cancer cells, at least in part by inhibiting Akt/mTOR/SREBP1 pathway-mediated lipid metabolism, indicating that CAPE may be an effective substance to assist in the treatment of breast cancer.
05:50
Eat This to Think Better for the Next Six Hours -- and Beyond GreenMedInfo
If you eat this sweet snack in the morning, you may enjoy better brain function for the rest of the day -- perfect if you know you have an important project or exam in the next few hours.
05:49
Eat This to Think Better for the Next Six Hours -- and Beyond GreenMedInfo
Visit our Re-post guidelines
If you eat this sweet snack in the morning, you may enjoy better brain function for the rest of the day -- perfect if you know you have an important project or exam in the next few hours.
Important work presentation on the schedule? Big exam coming up? During an ordinary day, your brain performance will gradually decrease as you become cognitively fatigued, possibly leaving you in a fog the moment you need your brain to be at its best.
05:46
Caffeic acid phenethyl ester mitigates cognitive impairment in aged mice following anesthesia and surgery. GreenMedInfo
PMID: Antioxidants (Basel). 2023 Mar 13 ;12(3). Epub 2023 Mar 13. PMID: 36978961 Abstract Title: Caffeic Acid Phenethyl Ester Suppresses Oxidative Stress and Regulates M1/M2 Microglia Polarization via Sirt6/Nrf2 Pathway to Mitigate Cognitive Impairment in Aged Mice following Anesthesia and Surgery. Abstract: Postoperative cognitive dysfunction (POCD) is a severe neurological complication after anesthesia and surgery. However, there is still a lack of effective clinical pharmacotherapy due to its unclear pathogenesis. Caffeic acid phenethyl ester (CAPE), which is obtained from honeybee propolis and medicinal plants, shows powerful antioxidant, anti-inflammatory, and immunomodulating properties. In this study, we aimed to evaluate whether CAPE mitigated cognitive impairment following anesthesia and surgery and its potential underlying mechanisms in aged mice. Here, isoflurane anesthesia and tibial fracture surgery were used as the POCD model, and H2O2-induced BV2 cells were established as the microglial oxidative stress model. We revealed that CAPE pretreatment suppressed oxidative stress and promoted the switch of microglia from the M1 to the M2 type in the hippocampus, thereby ameliorating cognitive impairment caused by anesthesia and surgery. Further investigation indicated that CAPE pretreatment upregulated hippocampal Sirt6/Nrf2 expression after anesthesia and surgery. Moreover, mechanistic studies in BV2 cells demonstrated that the potent effects of CAPE pretreatment on reducing ROS generation and promoting protective polarization were attenuated by a specific Sirt6 inhibitor, OSS_128167. In summary, our findings opened a promising avenue for POCD prevention through CAPE pretreatment that enhanced the Sirt6/Nrf2 pathway to suppress oxidative stress as well as favor microglia protective polarization.
05:35
Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy. GreenMedInfo
PMID: Int J Mol Med. 2023 Jun ;51(6). Epub 2023 Apr 28. PMID: 37114562 Abstract Title: Berberine blocks inflammasome activation and alleviates diabetic cardiomyopathy via the miR18a3p/Gsdmd pathway. Abstract: Diabetic cardiomyopathy (DCM) is a cardiovascular disease which has been reported as a major cause of mortality worldwide for several years. Berberine (BBR) is a natural compound extracted from a Chinese herb, with a clinically reported antiDCM effect; however, its molecular mechanisms have not yet been fully elucidated. The present study indicated that BBR markedly alleviated DCM by inhibiting IL1secretion and the expression of gasdermin D (Gsdmd) at the posttranscriptional level. Considering the importance of microRNAs (miRNAs/miRs) in the regulation of the posttranscriptional process of specific genes, the ability of BBR to upregulate the expression levels of miR18a3p by activating its promoter (1,000/500) was examined. Notably, miR18a3p targeted Gsdmd and abated pyroptosis in high glucosetreated H9C2 cells. Moreover, miR18a3p overexpression inhibited Gsdmd expression and improved biomarkers of cardiac function in a rat model of DCM. On the whole, the findings of the present study indicate that BBR alleviates DCM by inhibiting miR18a3pmediated Gsdmd activation; thus, BBR may be considered a potential therapeutic agent for the treatment of DCM.
05:31
Momordica charantia reduced ovarian ischemia - reperfusion injury by suppressing APAF-1 expression. GreenMedInfo
PMID: Eur Rev Med Pharmacol Sci. 2023 Mar ;27(6):2182-2188. PMID: 37013735 Abstract Title: Momordica charantia reduced ovarian ischemia - reperfusion injury by suppressing APAF-1 expression. Abstract: OBJECTIVE: We investigate the effect of Momordica charantia (MC) against ovarian ischemia-reperfusion injury (IRI).MATERIALS AND METHODS: Forty-eight Sprague Dawley female rats were divided into 6 groups. 3 hours ischemia/3 hours reperfusion was conducted. Before and/or after IR, 600 mg/kg MC were introduced to rats via an orogastric tube. At the end of the experiment, total serum antioxidant/oxidant status (TAS/TOS) and Anti-Mullerian Hormone (AMH) level were measured. Ovarian histopathology and APAF-1 expression level were analyzed.RESULTS: TAS and AMH levels were the lowest, while TOS level and OSI were the highest in the IR group. TAS and AMH levels were higher, and TOS levels and OSI were lower in MC-treated groups compared to IR group. Follicular degeneration, granulosa and stromal cell degeneration, mononuclear cell infiltration and vascular congestion and dilatation were observed in the IR group. Ovarian histopathology was improved in groups that received MC extract. APAF-1 immune activity was intense in IR and MC+IR groups while decreased in the groups treated with MC extract after IRI. MC treatment downregulated APAF-1 protein after IRI.CONCLUSIONS: MC extract restored negative biochemical and histochemical changes caused by IRI due to its antioxidant properties and supported cell survival by suppressing APAF-1 expression.
05:26
Momordica charantia efficacy and safety on glucose metabolism in Korean prediabetes participants. GreenMedInfo
PMID: Food Sci Biotechnol. 2023 Apr ;32(5):697-704. Epub 2022 Dec 14. PMID: 37009042 Abstract Title: (bitter melon) efficacy and safety on glucose metabolism in Korean prediabetes participants: a 12-week, randomized clinical study. Abstract: This study was performed to investigate the effects of bitter melon extract (BME) on glucose metabolism, insulin resistance, and various metabolic parameters of participants with prediabetes. A 12-week randomized placebo-controlled clinical study was conducted with prediabetic patients. A total of 76 participants were randomly assigned to initiate the study. In the final analysis, 33 and 32 subjects were included in the BME and placebo groups, respectively. Results showed that 75 g oral glucose tolerance test (OGTT) blood glucose level decreased in BME group after 12 weeks. The glucose level after 30 min of glucose ingestion decreased significantly. The glucagon level in the BME group after 12 weeks significantly decreased 120 min after 75 g OGTT. These results suggested that bitter melon exhibits glucose-lowering effects through suppression of glucagon levels in people with prediabetes.
05:20
CHD Responds to Federal Judge Blocking Biden Administration From Contacting Social Media Platforms in First Amendment Lawsuit Children's Health Defense
Press Release
For Immediate Release
Washington, D.C. Judge Terry A. Doughty of the U.S. District Court for the Western District of Louisiana issued a preliminary injunction in Missouri v. Biden prohibiting multiple key Biden administration officials and agencies from having any contact with social media companies with the intent to discourage or censor speech protected by the First Amendment.
In his 155-page opinion, Judge Doughty wrote:
The right of free speech is a fundamental constitutional right that is vital to the freedom of our nation, and Plaintiffs have produced evidence of a massive effort by Defendants, from the White House to federal agencies, to suppress speech based on its content. Defendants alleged suppression has potentially resulted in millions of free speech violations.
Childrens Health Defense Chairman on leave Robert F. Kennedy Jr. is mentioned in the lawsuit regarding 2021 White House communications with Twitter requesting the removal of a Tweet from Kennedy regarding COVID-19 vaccines.
Kennedy responded to the judgment:
This is one of the most important First Amendment cases in our nations history. Missouri v. Biden concerns every American regardless of party affiliation, political ideology, personal beliefs or religion. Freedom of speech has been the central foundation stone of our democracy since our nations birth.
An American president has no right to wield White House power to silence his critics. These actions were anathema to our core American values and a disappointment to all those around the globe who see America as the worlds exemplary democracy.
CHD has two active lawsuits in front of Judge Daughty CHD, et al. v. The Washington Post, et al. and Kennedy, et al. v. Biden, et al.
Jed Rubenfeld, CHD lead counsel for the Plaintiffs, said:
The ruling in Missouri v. Biden is a tremendous victory for freedom of speech, recognizing and condemning unconstitutional federal involvement in social media censorship and specifically in the censorship of CHD and Bobby Kennedy Jr.
As the Supreme Court reaffirmed just days ago, If t...
04:54
Jul 6, Anxiety stomach Pains caused by possible cancer return The Abdominal Pain BlogKeeping You Updated On What Is New On The Site!
Diagnosed with Prostate Cancer 16 years ago. Over the last 2 years my PSA results have started to climb, therefore yesterday I had a full body bone scan
03:14
18 Medicinal Properties of Cucumbers GreenMedInfo
Visit our Re-post guidelines
Marvel over the humble cucumber with these 18 health benefits, which range from keeping your body cool and hydrated to helping prevent diseases such as diabetes
Eat them raw and you get a juicy crunch. Cucumbers, however, do more than just serve as a refreshing feature of salads, sandwiches, slaws, pickles, noodles, cocktails and more. This popular produce pick, a member of the Cucurbitaceae family along with melon, squash and pumpkins, has been used in traditional medicine since ancient times for its unnumbered health benefits.
03:00
What Does ChatGPT Say About MIA? Mad In America
I imagine that I am like many people when it comes to AI, which is that I dont really know what to make of it. The science fiction future that was envisioned with the dawn of the computer seems to have fully arrived, and now there is great speculation, and some degree of trepidation, about how it will remake our society and our sense of self.
As ChatGPTs intelligence is based on a scrubbing of an enormous amount of information from the Internet, I thought it could be intriguingand possibly revealingto have a chat with this AI machine about psychiatry and its treatments. My supposition that its comments will reflect in some fashion the noise that exists on the Internet about a certain subject.
My first request to ChatGPT was write an essay about the Mad in America website. I presumed that this would generate an essay that relied mostly on data scrubbed from our website and podcasts, and thus the essay might tell of the image we project to the world.
Here is the essay that ChatGPT produced in a matter of seconds:
Title: Mad in America: Challenging the Paradigm of Mental Health
Introduction:
In recent decades, the field of mental health has witnessed a growing movement known as Mad in America. This movement questions the prevailing paradigm of mental illness and challenges the assumptions and practices of the mental health system. Mad in America advocates argue for a shift in focus from psychiatric labels and medication-centric approaches toward a more holistic, person-centered, and socially contextual understanding of distress. This essay will explore the key tenets and criticisms of Mad in America, highlighting its...
02:48
Golden Kvass Recipe The Healthy Home Economist
Traditional kvass recipe using golden beets for a sweeter and less earthy flavor. Loaded with probiotics, trace minerals, and enzymes, it is the perfect health tonic to sip first thing in the morning. One of the very first fermented beverage recipes published on this blog (in 2010!) was a recipe for red beet kvass. Ive
The post Golden Kvass Recipe appeared first on The Healthy Home Economist.
02:36
How to Treat Varroa Mites Naturally (without burning beehives!) The Healthy Home Economist
How to eliminate a varroa mite infestation naturally while preserving the safety of the bees and integrity of the colony. As a new beekeeper, I was horrified to recently learn of an inflexible government policy in Australia that is mandating the burning of beehives with gasoline for potential varroa mite infestations. This is the case
The post How to Treat Varroa Mites Naturally (without burning beehives!) appeared first on The Healthy Home Economist.
02:34
02:30
PFAS Report puts FDA in Cross-Hairs Alliance for Natural Health USA Protecting Natural Health
Our report showing supermarket kale to be contaminated with toxic chemicals is getting picked up far and wide. Help us maintain the momentum and call for a ban on toxic PFAS forever chemicals. Action Alert!
Last week, we launched a national campaign on the back of our pilot study showing 7 of 8 supermarket kale samples to be contaminated with PFAS forever chemicals, suggesting much wider contamination of our food supply with these chemicals than the FDA wants to acknowledge. We know PFAS, or polyfluoroalkyl substances, are already being found in alarming amounts in drinking water, in the air, and in thousands of consumer products. We also know that they persist in the environment, accumulate in the human body, and are linked to a host of negative health outcomes. Thats why weve used our pilot study as a springboard to launch a campaign calling for the federal government to issue a ban on the over 12,000 chemicals that fall under the PFAS category.
Our study has already started making waves. It has been picked up by news outlets around the world, including major outlets like The Guardian, The New York Post, and HealthNews. Rob Verkerk, PhDfounder of the Alliance for Natural Health and ANH-USAs Executive and Scientific Director who has headed up the workwas also on Ron Hoffman, MDs Intelligent Medicine podcast to discuss the report. You can find a comprehensive list of media outlets which have covered and discussed our report below.
U.S. regulatory agencies have proven themselves incapable or unwilling to meaningfully address the extensive PFAS contamination. We need to create a groundswell of grassroots support for a ban on PFAS chemicals as soon as possible. Visit the reports landing page to send a message to your state and federal...
02:29
Hormone Replacement Therapy in Jeopardy Alliance for Natural Health USA Protecting Natural Health
The screws continue to tighten on compounded bioidentical hormone replacement therapy (cBHRT), the future of which is in peril. We need your help to support a US Senate sign-on letter telling the FDA NOT to limit access to these treatments. Action Alert!
A letter being circulated in the Senate by US Senators Tammy Baldwin (D-WI) and Roger Marshall (R-KS) urges the FDA to enact policies that allow patients to continue using compounded bioidentical hormone replacement therapy (cBHRT). These actions are necessary because FDA is threatening to ban compounded bioidentical hormones like estriol, progesterone, testosterone, and estradiol. Millions of women rely on these medicines to manage the symptoms of menopause, overcome fertility challenges, or treat other hormonal imbalances. These women need cBHRT to stay healthy and cannot, or do not want to, use the FDA-approved versions of these hormones. We must urge our Senators to support this letter.
Earlier this year we supported a House of Representatives letter led by Representatives Jennifer Wexton (D-VA) and Michael Burgess (R-TX). Thanks to your help, ANH and other stakeholders were able to get 23 other representatives to sign on to the letter, signaling their support for cBHRT. We need to generate similar success in the Senate to build momentum around this issue.
To recap how we got here: The FDA is in the process of deciding whether it will allow patients to continue to access compounded bioidentical estriol, progesterone, testosterone, and estradiol. It is clear to anyone paying attention that the FDA is seeking a ban on these medicines.
When ANH and other stakeholders organized widespread grassroots opposition to a ban on estriol and other compounded hormones, the FDA asked the National Academies of Sciences, Engineering, and Medicine (NASEM) to review the clinical utility of treating patients with cBHRT. The intention of this review was clear: the FDA orchestrated what would look to outsiders like an impartial review of cBHRT to give itself cover to ban these medicines. And right on cue, NASEMs report found that treating patients with cBHRT was a public health concern.
Yet NASEMs review was anything but impartial. Conspicuously missing from the committee was anyone with an expertise on how compounded bioidentical hormones are used to treat patients. Several members had ties to pharmaceutical companies which would benefit from compounded medicines being eliminated. The FDA...
02:26
Free Speech Victory! Court Pushes Back Against Censors Alliance for Natural Health USA Protecting Natural Health
A federal judge has found that the Biden Administration likely violated the First Amendment by working with major social media companies to censor speech it didnt like. Action Alert!
U.S. District Court Judge Terry Doughty issued a preliminary injunction barring federal officials and agencies, including the Surgeon General, the Secretary of Health, the Justice Department, and the FBI, from having any contact with social media firms for the purpose of discouraging or removing First Amendment-protected speech. This is a result of lawsuits lodged against the Biden Administration from the Attorneys General of Louisiana and Missouri alleging that the Administration pressured social media companies to remove misinformation about COVID and other issues. This is a welcome victory in what has been a steady march toward more and more censorship of information that contradicts the official narratives coming from the government or other powers on high.
In a 155-page opinion, Judge Doughty summarized what many of us in the natural health community have been pointing out for some time: During the COVID-19 pandemic, a period perhaps best characterized by widespread doubt and uncertainty, the United States Government seems to have assumed a role similar to an Orwellian Ministry of Truth. He notes a wide range of opinions that were suppressed, including opposition to COVID vaccines, masking, lockdowns, and the lab-leak theory.
The Biden Administration will likely appeal this decision to the 5th US Circuit Court of Appeals.
This is an important victory. We learned a great deal more about this widespread censorship campaign when Elon Musk bought Twitter and released a massive number of documents to independent journalists. The Twitter Files detailed the close coordination between Twitter and other platforms and the US government in censoring speech. As journalist Matt Taibbi put it,
When we got into the Files, we were caught off guard. The content-policing system was more elaborate and organized than any of us imagined. A communications highway had been built linking the FBI, the Department of Homeland Security, and the Office of the Director of National Intelligence with Twitter, Facebook, Google, and a slew of other platforms. Among other things this looked more like a cartel than a competitive me...
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Thursday, 06 July
22:00
The effects of vitamin D supplementation on major cardiac events Science-Based Medicine
A large randomized controlled trial of vitamin D supplementation generates good data to show there is likely no benefit.
The post The effects of vitamin D supplementation on major cardiac events first appeared on Science-Based Medicine.20:07
Adults With Autism Need Everything Students Needed and More Age of Autism The Rebel Alliance!
This meme stopped me in my tracks. It's so true. Adults with autism
are being disappeared, even as the number of those over 18 grows.
Its a dirty secret. After 22, families are on special needs.
Quality care. Meaningful days. Safe nights. Required, skilled care,
not the take it or leave it system in place now. Students
with autism have trained teachers and staff working with them.
Adults with autism have few trained people around them to help them
hold down a job, live independently, attend a day program or live
in shared housing. It's bad and going to get worse. Because parents
are growing older. And their parents are already quite old. This
sandwich generation is the toughest to imagine. Yet here we are. No
flag. No special color. No puzzle piece. No social outrage. We're
too complicated. Too nuanced. TOO REAL.
###
Order today, from Skyhorse Publishing.
The Wuhan Cover Up How Health
Officials Conspired with the Chinese Military to Hide the Origins
of COVID-19 (Childrens Health Defense)
The Wuhan Cover-Up pulls back the curtain on how the US
government's increase in biosecurity spending after the 2001 terror
attacksfacilitated by Dr. Anthony Fauci, director of the National
Institute of Allergy and Infectious Diseases (NIAID)set in motion a
plan to transform the NIAID into a de facto Defense Department
agency.
While Dr. Fauci zealously funded and pursued gain-of-function
research, concern grew among some scientists and government
officials about the potential for accidental or deliberate release
of weaponized viruses from labs that might trigger worldwide
pandemics. A moratorium was placed on this resear...
11:07
A comprehensive review of herbal supplements used for persistent symptoms attributed to lyme disease. GreenMedInfo
PMID: Integr Med (Encinitas). 2023 Mar ;22(1):30-38. PMID: 37101730 Abstract Title: A Comprehensive Review of Herbal Supplements Used for Persistent Symptoms Attributed to Lyme Disease. Abstract: CONTEXT: Lyme disease is the most common, tick-borne disease in the USA. While most patients successfully recover with antibiotics, some patients experience persistent symptoms for months to years. Patients who attribute chronic symptoms to Lyme disease commonly use herbal supplements. The complexity, variability in dose and formulation, and lack of data for these herbal compounds make it difficult to assess their efficacy and safety.OBJECTIVE: This review examines the evidence for the antimicrobial activity, safety, and drug-drug interactions of 18 herbal supplements that patients commonly use for treatment of persistent symptoms attributed to Lyme disease.DESIGN: The research team performed a narrative review by searching the PubMed, Embase, Scopus, Natural Medicines databases, and NCCIH website. The search used the keywords for 18 herbal compounds: (1) andrographis (Andrographis paniculate), (2) astragalus (Astragalus propinquus), (3) berberine, (4) cat's claw bark (Uncaria tomentosa), (5) cordyceps (Cordyceps sinensis), (6) cryptolepis (Cryptolepis sanguinolenta), (7) Chinese skullcap (Scutellaria baicalensis), (8) garlic (Allium sativum), (9) Japanese knotwood (Polygonum cuspidatum), (10) reishi mushrooms (Ganoderma lucidum), (11) sarsaparilla (Smilax medica), (12) Siberian ginseng (Eleutherococcus senticosus), (13) sweet wormwood (Artemisia annua), (14) teasle root (Dipsacus fullonum), (15) lemon balm (Melissa officinalis), (16) oil of oregano (Origanum vulgare), (17) peppermint (Mentha x piperita), and (18) thyme (Thymus vulgaris). The team also searched for terms related to protocols, including Dr. Rawls' protocol and the Buhner protocol.SETTING: University of Maryland Medical Center, Baltimore MD.RESULTS: Seven of the 18 herbs reviewed had evidence for in-vitro activity against. These compounds included: (1) cat's claw (2) cryptolepis, (3) Chinese skullcap, (4) Japanese knotweed, (5) sweet wormwood, (6) thyme, and (7) oil of oregano. With the exception of oil of oregano these compounds also have anti-inflammatory activity. In vivo data and clinical trials are lacking. Clinicians should be cautious as many of the identified compounds have drug interactions and additive effects that could lead to increased risks for bleeding, hypotension, and hypoglycemia.CONCLUSIONS: Many of the herbs that alternative and integrative practitioners use to treat Lyme disease have anti-inflammatory effects that may contribute to patients' perceptions of symptomatic improvement. Some herbs have limited demonstrated anti-borrelial activity in vitro, but in-vivo data and clinical trial...
10:00
Is This a Natural Option for Harmful Skinny Injections? Articles
Berberine is a naturally occurring compound found in certain plants, which some are calling "natures Ozempic."1 It is a once-weekly injectable diabetes medication that has grown in popularity as a weight loss product. However, as popularity has grown, so have shortages.2 In response, some are posting information about alternatives, such as other diabetic drugs, generic Ozempic (semaglutide) made at compounding pharmacies or berberine.
Prescriptions for semaglutide have doubled since mid-2021, rising to more than 1.2 million. In April 2023, a spokesperson for Novo Nordisk, maker of semaglutide, said the drugs are now available in pharmacies nationwide. Semaglutide is sold under the name Ozempic as a diabetes drug and under the name Wegovy as a weight loss prescription drug.
Berberine has received a lot of media attention as it gains momentum on social media as a weight loss supplement. Berberine is a compound that's extracted from goldenseal, barberry, Oregon grape and tree turmeric. It has traditionally been used in Ayurvedic medicine and traditional Chinese medicine3 for nearly 2,000 years.4
Recent research has analyzed the effect berberine may have on hypertension and insulin resistance. The yellow-colored alkaloid has antibacterial, anti-inflammatory, antiproliferative, antidiarrheal, antineoplastic, antidiabetic and immune-enhancing properties.5
However, the property that appears to have piqued peoples interest is the weight loss potential. While the news media does offer some information about berberine in relation to Ozempic and Wegovy, the vast majority of the information cautions readers.6
The list of potential issues includes that supplements are not reviewed or approved by the FDA, may not be safe for consumption and that people who experience weight loss with berberine should stop immediately and consult with their physician as it suggests the supplement may have been adulterated.
Berberine Helps Regulate Blood Sugar and Aids Gut Microbiome
Research data shows that berberine helps to regulate blood sugar and may help with weight loss. A 2022 systematic review of the literature7 evaluated randomized controlled trials of adults who were given berberine supplementation. The pooled results demonstrated that berberine did reduce insulin levels and the optimal dose given in these studies was 1 gram per day.
...Suicide Is on the Rise Know the Warning Signs Articles
Editor's Note: This article is a reprint. It was originally published June 21, 2018.
The suicides of fashion designer Kate Spade and celebrity chef and TV personality Anthony Bourdain,1 which occurred within days of each other, in 2018 reignited a much-needed public discussion about suicide, mental illness and its treatment. As noted by Dr. Anne Schuchat, then-principal deputy director of the U.S. Centers for Disease Control and Prevention, depression "is not a condition that is related to success or failure. No one is immune."2
Statistics also reveal suicide rates have risen sharply across the U.S. since the early 2000s, prompting health authorities to call for "a comprehensive approach to addressing depression."3 Since the pandemic suicide in 2023 is the 11th leading cause of death in the U.S., with an average132 suicides per day.4
However, while a number of headlines scream for new drug treatment,5 I believe we'll get nowhere fast unless we start to address mental health from a more holistic perspective. It seems quite clear that antidepressants, in addition to not working very well (or in some cases at all), are actually part of the problem thanks to their side effects.
Meanwhile, nutritional deficiencies, a decline in social interaction brought about by increasing reliance on social media and technology, excessive exposure to electromagnetic fields (EMFs), lack of sleep, "lack of life purpose" or spiritual connection, and chronic, unresolved stress are just some of the factors that can contribute to depression, none of which can be addressed by new or more drugs.
Specific medical conditions, such as cancer, heart disease, diabetes and stroke are also linked to a higher risk of major depressive disorder.
Spade's Suicide Took Those Closest to Her by Surprise
According to Spade's husband and business partner, Andy Spade, Kate had struggled with depression and anxiety for several years, and was taking medication for these issues.6,7 When she killed herself, the couple had been separated 10 months, but lived within blocks of each other...
How China Is Destroying American Farmland Articles
North Carolina is the home of more than 2,000 large-scale hog farms, primarily clustered in the rural eastern region of the state. As illustrated in the Vox video above, factory scale hog farming takes a tremendous toll on the surrounding environment, as hog excrement ends up polluting waterways, land and air.
More than 200 of these North Carolina hog farms are owned or operated by Smithfield Foods,1 the largest pork producer in the world, which in 2013 was acquired by the WH Group, a Chinese pork conglomerate that had previously been accused of feeding its hogs illegal chemicals.2
But as reported by Rolling Stone magazine in 2018, that wasnt the only safety concern raised by the sale:3
The Chinese government had a track record of using nominally private entities as proxies for state power ... In 2011 ... the government issued a plan directing Chinese companies to buy foreign food producers and farmland. In two years, Chinese nationals went from owning $81 million worth of American farmland to nearly $1.4 billion ...
The investigative news organization Reveal uncovered documents showing that WH Group receives guidance from the government, which a company executive explained was because pork is considered a national-security issue in China ...
Part of what made the company such an attractive target is that its about 50% cheaper to raise hogs in North Carolina than in China. This is due to less-expensive pig-feed prices and larger farms, but its also because of loose business and environmental regulations ... which have made the U.S. an increasingly attractive place for foreign companies to offshore costly and harmful business practices.
China Dumps Its Agricultural Waste in the US
In years past, the U.S. outsourced dirty industry processes to poorer countries. Today, China is doing the same, and its treating the U.S. as a developing nation. Granted, U.S. environmental policies which have gotten increasingly lax over time due to regulatory capture by industry are what allows for this hostile takeover in the first place.
Believe it or not, China doesnt allow hog waste to be sprayed on fields as a means of disposal, as is routinely done here in the U.S. In China, hog farmers are forced to spend big bucks on wastewater treatment, digeste...
09:35
Citing 'Orwellian' Tactics, Federal Judge Orders White House to Stop Censoring Americans' Social Media Posts GreenMedInfo
Judge Terry Doughty said there is "substantial evidence" the government violated the First Amendment by engaging in a large-scale censorship
09:34
Citing 'Orwellian' Tactics, Federal Judge Orders White House to Stop Censoring Americans' Social Media Posts GreenMedInfo
Originally published on www.childrenshealthdefense.org by Michael
Nevradakis, Ph.D.
In his 155-page ruling, Judge Terry Doughty said there is "substantial evidence" the government violated the First Amendment by engaging in a large-scale censorship campaign targeting content that questioned or countered establishment narratives on COVID-19.
07:08
Popular Benzo Drugs Linked to Suicide, Brain Damage Even If You Stop Taking Them: Study Mad In America
From The New York Post: Over 30 million Americans a year use benzodiazepines, or benzos, including Xanax, Valium, Ativan and Klonopin. Benzodiazepines are prescribed to treat anxiety disorders, insomnia, muscle spasms, schizophrenia, bipolar disorder, seizures and epilepsy. But this widely used class of drugs is linked to severe side effects and life impacts that can last for years even after people have stopped taking the drugs a new study finds.
. . . The researchers have coined the term BIND, or benzodiazepine-induced neurological dysfunction, to describe the long-lasting effects of benzo use. Though BIND is a new term and the condition is not yet well-defined or universally accepted by doctors, the study authors believe it could be a result of brain changes resulting from benzodiazepine use. BIND could occur in roughly one in five long-term users of benzodiazepines.
***
Back to Around the Web
The post Popular Benzo Drugs Linked to Suicide, Brain Damage Even If You Stop Taking Them: Study appeared first on Mad In America.
07:04
This review summarizes the hepatoprotective properties of G. lucidum. GreenMedInfo
PMID: Nutrients. 2023 Apr 13 ;15(8). Epub 2023 Apr 13. PMID: 37111092 Abstract Title: : Novel Insight into Hepatoprotective Potential with Mechanisms of Action. Abstract: () has been widely used for its health benefits as an edible and traditional medicinal mushroom for thousands of years in Asian countries. It is currently used as a nutraceutical and functional food owing to its major bioactive compounds, polysaccharides and triterpenoids.exhibits a broad range of hepatoprotective impacts in various liver disorders, such as hepatic cancer, nonalcoholic fatty liver disease (NAFLD), alcohol-induced liver disease, hepatitis B, hepatic fibrosis, and liver injury induced by carbon tetrachloride (CCl4) and-amanitin.protects the liver through a broad range of mechanisms that include the modulation of liver Phase I and II enzymes, the suppression of-glucuronidase, antifibrotic and antiviral actions, the regulation of the production of nitric oxide (NO), the maintenance of hepatocellular calcium homeostasis, immunomodulatory activity, and scavenging free radicals.could signify an encouraging approach for the management of various chronic hepatopathies, and its potential mechanisms make it a distinctive agent when used alone or with other drugs and applied as a functional food, nutraceutical supplement, or adjuvant to modern medicine. This review summarizes the hepatoprotective properties ofwith its various mechanisms of action on different liver ailments. Biologically active substances derived fromare still being studied for their potential benefits in treating different liver ailments.
06:54
Anthony Holland PhD: Destroying Cancer Cells with Music Frequencies Medical Kidnap
by Brian Shilhavy
Editor, Health Impact News
If you are someone who has contributed charitable funds to help find a cure for cancer for the past 50+ years, I am sorry to inform you that you have probably been defrauded by being fooled into contributing funds to Big Pharma and cancer drug research, where a cancer drug is considered successful if it can extend the life of a cancer patient for up to 5 years.
There are no pharmaceutical products that actually cure cancer, because treating cancer is too profitable of an industry for Big Pharma to allow cures. See:
The Cancer Industry is Too Prosperous to Allow a Cure
But the fact is that there are literally hundreds of cures for cancer worldwide, although the FDA has outlawed almost all of them in the U.S. when they became too effective and interfered with drug profits.
A great documentary to watch if this is new topic to you, is Cancer: The Forbidden Cures The Original Big Pharma Playbook Long Before COVID.
This is on our Bitchute Channel.
For a review of unapproved but effective cancer cures that we published back in 2014, see:
Unapproved but Effective Cancer Cures
Another person who has had success in curing cancer with ongoing research here in 2023, is Anthony G. Holland, who has a PhD in musical arts, is a renowned composer who has conducted at Carnegie Hall, and has been a Professor of Music and Director of Music Technology at Skidmore College for over 3 decades. (Bio here.)
Dr. Holland gained some attention to his work with a presentation in 2013 in a TED Talk, titled Shattering cancer with resonant frequencies, that has over 2 million views and is, remarkably, still up on YouTube:
06:53
Anthony Holland PhD: Destroying Cancer Cells with Music Frequencies Vaccine Impact
by Brian Shilhavy
Editor, Health Impact News
If you are someone who has contributed charitable funds to help find a cure for cancer for the past 50+ years, I am sorry to inform you that you have probably been defrauded by being fooled into contributing funds to Big Pharma and cancer drug research, where a cancer drug is considered successful if it can extend the life of a cancer patient for up to 5 years.
There are no pharmaceutical products that actually cure cancer, because treating cancer is too profitable of an industry for Big Pharma to allow cures. See:
The Cancer Industry is Too Prosperous to Allow a Cure
But the fact is that there are literally hundreds of cures for cancer worldwide, although the FDA has outlawed almost all of them in the U.S. when they became too effective and interfered with drug profits.
A great documentary to watch if this is new topic to you, is Cancer: The Forbidden Cures The Original Big Pharma Playbook Long Before COVID.
This is on our Bitchute Channel.
For a review of unapproved but effective cancer cures that we published back in 2014, see:
Unapproved but Effective Cancer Cures
Another person who has had success in curing cancer with ongoing research here in 2023, is Anthony G. Holland, who has a PhD in musical arts, is a renowned composer who has conducted at Carnegie Hall, and has been a Professor of Music and Director of Music Technology at Skidmore College for over 3 decades. (Bio here.)
Dr. Holland gained some attention to his work with a presentation in 2013 in a TED Talk, titled Shattering cancer with resonant frequencies, that has over 2 million views and is, remarkably, still up on YouTube:
06:43
Neuroprotective, neurogenic, and anticholinergic evidence of Ganoderma lucidum cognitive effects. GreenMedInfo
PMID: Med Res Rev. 2023 Apr 13. Epub 2023 Apr 13. PMID: 37052237 Abstract Title: Neuroprotective, neurogenic, and anticholinergic evidence of Ganoderma lucidum cognitive effects: Crucial knowledge is still lacking. Abstract: Ganoderma lucidum is a mushroom that has been widely used for centuries in Asian countries for its antiaging properties. It is popularly known as "Ling Zhi," "Reishi," and "Youngzhi," and because of its benefits, it is known as the "immortality mushroom." Pharmacological assays have revealed that G. lucidum ameliorates cognitive impairments through inhibition of-amyloid and neurofibrillary tangle formation, antioxidant effect, reduction of inflammatory cytokine release and apoptosis, genic expression modulation, among other activities. Chemical investigations on G. lucidum have revealed the presence of metabolites such as triterpenes, which are the most explored in this field, as well as flavonoids, steroids, benzofurans, and alkaloids; in the literature, these have also been reported to have mnemonic activity. These properties of the mushroom make it a potential source of new drugs to prevent or reverse memory disorders, as actual medications are able to only alleviate some symptoms but are unable to stop the progress of cognitive impairments, with no impact on social, familiar, and personal relevance. In this review, we discuss the cognitive findings of G. lucidum reported in the literature, converging the proposed mechanisms through the several pathways that underlie memory and cognition processes. In addition, we highlight the gaps that deserve particular attention to support future studies.
06:29
RFK Jr is still wrong vaccines do NOT cause autism Skeptical Raptor
The Skeptical Raptor, stalking pseudoscience in the internet jungle.
Despite the false claims from Robert F Kennedy Jr and other anti-vaxxers, the scientific facts is vaccines do not cause autism.
06:25
Anthony Holland PhD: Destroying Cancer Cells with Music Frequencies Health Impact News
by Brian Shilhavy
Editor, Health Impact News
If you are someone who has contributed charitable funds to help find a cure for cancer for the past 50+ years, I am sorry to inform you that you have probably been defrauded by being fooled into contributing funds to Big Pharma and cancer drug research, where a cancer drug is considered successful if it can extend the life of a cancer patient for up to 5 years.
There are no pharmaceutical products that actually cure cancer, because treating cancer is too profitable of an industry for Big Pharma to allow cures. See:
The Cancer Industry is Too Prosperous to Allow a Cure
But the fact is that there are literally hundreds of cures for cancer worldwide, although the FDA has outlawed almost all of them in the U.S. when they became too effective and interfered with drug profits.
A great documentary to watch if this is new topic to you, is Cancer: The Forbidden Cures The Original Big Pharma Playbook Long Before COVID.
This is on our Bitchute Channel.
For a review of unapproved but effective cancer cures that we published back in 2014, see:
Unapproved but Effective Cancer Cures
Another person who has had success in curing cancer with ongoing research here in 2023, is Anthony G. Holland, who has a PhD in musical arts, is a renowned composer who has conducted at Carnegie Hall, and has been a Professor of Music and Director of Music Technology at Skidmore College for over 3 decades. (Bio here.)
Dr. Holland gained some attention to his work with a presentation in 2013 in a TED Talk, titled &...
06:15
Oral administration of human FGF21 expressed by mycelium of Cordyceps militaris improves blood glucose and lipid in type II diabetes mellitus. GreenMedInfo
PMID: Cell Mol Biol (Noisy-le-grand). 2022 Sep 30 ;68(10):54-62. Epub 2022 Sep 30. PMID: 37114272 Abstract Title: Oral administration of human FGF21 expressed by mycelium of Cordyceps militaris improves blood glucose and lipid in type II diabetes mellitus. Abstract: The purpose of this study was to express human FGF21 (hFGF21) using Cordyceps militaris (C. militaris) as a bioreactor and to observe its hypoglycemic and lipid-lowering effects on type II diabetes. The recombinant plasmid pCB130-hFGF21 was transformed into C. militaris to form recombinant recombinant C. militaris (RhFGF21), the stability of RhFGF21 in vitro and in vivo was analyzed. RhFGF21 significantly promoted glucose uptake in a dose-dependent manner in adipocytes and increased the levels of p-PLC, p-FRS2 and p-ERK, which was consistent with the commercial hFGF21. In animal experiments, oral RhFGF21 obviously reduced the levels of glucose, insulin, TG, T-CHO, NEFA, and LDL-C in the blood, the contents of ALT, AST, TNF-, MCP-1, F4/80, CD68 and CD11b in the fatty liver, and the apoptosis of pancreatic cells. C. militaris is an excellent carrier that can stabilize the expression of hFGF21 and protect the biological activity of hFGF21 during oral administration, which provides a theoretical basis for the development of hFGF21 oral preparations for type II diabetes.
05:46
Editors of public health journal resign over differences with publisher Retraction Watch
The co-editors in chief and most editorial board members of the journal Critical Public Health have resigned their roles to start a new, independent journal, citing differences with their publisher, Taylor & Francis.
While there are inevitable tensions for a critically oriented scholarly journal that is also a commodity marketed by a commercial publisher, over the last year or so it has become increasingly difficult to hold together these two different versions of the journal, co-editors Judith Green of the University of Exeter in the UK and Lindsay McLaren of the University of Calgary in Canada said in a press release announcing the mass resignation.
It is simply a relationship that hasnt worked out and we need to find other ways to continue the spirit of the community, McLaren told us.
Earlier this year, the entire editorial boards of the open-access Elsevier journals NeuroImage and NeuroImage: Reports resigned to start a new, non-profit journal after the publisher rebuffed their request to reduce the journals fees for authors to publish their work. Editors of another Elsevier journal, Design Studies, have also threatened to resign following the publisher replacing the editor-in-chief and pushing the editorial team to publish more papers.
The press release and resignation letter from the Critical Public Health editors posted online cited a 2021 editorial by Green, McLaren, and two other board members discussing the history of the journal and consolidation in the academic publishing industry that led to Taylor & Francis owning the journal. They also cited the publisher pushing the editors to move the journal from a hybrid subscription/open-access model to a fully open-access model...
02:00
The Wuhan Cover-Up: How US Health Officials Conspired with the Chinese Military to Hide the Origins of COVID-19 Children's Health Defense
Gain-of-function experiments are often conducted to deliberately develop highly virulent, easily transmissible pathogens for the stated purpose of developing preemptive vaccines for animal viruses before they jump to humans. More insidious is the dual use nature of this research, specifically directed toward bioweapons development.
The Wuhan Cover-Up pulls back the curtain on how the U.S. governments increase in biosecurity spending after the 2001 terror attacks facilitated by Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID) to set in motion a plan to transform the NIAID into a de facto Defense Department agency.
While Fauci zealously funded and pursued gain-of-function research, concern grew among some scientists and government officials about the potential for accidental or deliberate release of weaponized viruses from labs that might trigger worldwide pandemics. A moratorium was placed on this research, but true to form, Fauci found ways to continue unperturbed outsourcing some of the most controversial experiments offshore to China and providing federal funding to Wuhan Institute of Virologys (WIVs) leading researchers for gain-of-function studies in partnership with the Chinese military and the Chinese Communist Party.
Robert F. Kennedy, Jr., whose meticulously researched and rigorously sourced analysis, leads readers on a staggering journey to learn about the:
- Key enablers and henchmen pushing for gain-of-function research
- Economic motives behind gain-of-function research.
- Successfully engineered chimeric viruses that can infect and kill humans.
- Coordinated effort to silence speculation of COVID-19s laboratory genesis.
- Complicity of scientific journals to hide the origins of COVID-19.
- Role of the Wuhan Institute of Virology in Chinas biowarfare/biodefense program.
- Relationships between U.S. health, military and intelligence bureaucracies and scientists and their Chinese counterparts.
- Roles of Bill Gates and Sir Jeremy Farrar in helping to orchestrate Chinas global cover-up.
The Wuhan Cover-Up unveils a global U.S.-Chinese conspiracy of epic proportion and lethal consequence.
The post The Wuhan Cover-Up: How US Health Officials Conspired with the Chinese Military to Hide the Origins of COVID-19 appeared first on Children's Health Defense.
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Wednesday, 05 July
05:02
Scars by Marlowe Dickens Mad In America
Once I had a dream, I awoke in a
Hospital bed with my family and friends all around me.
My wrists were bound in bandages
And they all wept
Why? Why would he do it?
But I did not. He ripped off the bandages to reveal bare
wrists.
See, I did not do it.
But they continued to weep.
Look, I have no scars, it was not me.
He had been beautiful, why could he not see?
But I could not see the scars
For they were in me.
****
Back to Poetry Gallery
The post Scars by Marlowe Dickens appeared first on Mad In America.
Saturday, 01 July
01:48
Navy Commander Tells All in New Release From CHD Books on the Illegal Military COVID Vaccine Mandate Children's Health Defense
Press Release
For Immediate Release
Washington, D.C. On July 29, 2021, President Biden directed the Department of Defense to add COVID-19 vaccines to the list of military requirements. On Aug. 24, the day after the FDA licensed the Comirnaty vaccine, Secretary of Defense Lloyd Austin mandated COVID-19 vaccinations for every service member. The military illegally enforced this mandate by withholding the fully licensed product, ignoring service members rights to refuse experimental medicines. Active-duty Navy Commander Robert A. Green Jr. chronicles this unprecedented travesty of justice in Childrens Health Defenses (CHDs) new book to be released on July 4, Defending the Constitution Behind Enemy Lines: A Story of Hope for Those Who Love Liberty.
A devout Catholic and father of seven, Green was banned from his building and fired from his position leading a 650-person unit after he refused the COVID vaccine for religious reasons. In addition to authoring numerous internal Navy complaints documenting unlawful actions on the part of his superiors, Green supplied multiple whistleblower reports to Congress.
The automatic denial of religious exemptions in the military was so egregious that in 2022, judges in non-military courts hearing lawsuits on behalf of service members granted preliminary injunctions against the Navy, the Air and Space Forces, and the Marine Corps. The National Defense Authorization Act for Fiscal Year 2023 finally put an end to the mandate, but this did nothing for the many service members who had already been penalized for refusing what turned out to be an unsafe and ineffective experimental drug.
Conscientious objectors lost promotions and positions and/or were involuntarily separated from the military, all while being denied their right to due process. Among them were Navy music...