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Sunday, 23 July
10:00
Evidence-Based Homeopathic Family Medicine "IndyWatch Feed Health"
Editor's Note: This article is a reprint. It was originally published December 2, 2018.
Homeopathy has been a form of medicine for hundreds of years. Dana Ullman, whose father was a medical doctor, a pediatrician and allergist, has dedicated a significant portion of his professional life to the practice of homeopathy. Ullman was introduced to this medical art as a junior at University of California (UC) Berkeley, in 1973.
"A Stanford-trained doctor and a male midwife created a group of people to study homeopathy together: three doctors, two nurses, two yoga teachers, a dentist and several laypeople. We met weekly for five years. Towards the end of that, I was honored to be arrested for practicing medicine without a license. That was in 1976.
We won an important court case settlement by differentiating medical care from health care. We made it clear that I wasn't treating a disease. I was treating a person with a disease.
The courts agreed that was a reasonable interpretation, and that as long as I have written contracts with my patients that differentiate medical care from health care, as long as I refer patients for medical care, which is not what I am providing, then it can work out. I've been doing that ever since," Ullman says.
Definition of Homeopathy
The principles of homeopathy were originally developed by Dr. Samuel Hahnemann (1755-1843), a German physician to the Royal family, and are based in the law of similars, also known as "like cures like."
"Homeopathy is a type of natural medicine that uses nano-doses, really small doses of plants, minerals, animals and chemicals," Ullman explains. "We look to find whatever toxicological symptoms that substance causes. Once you know what syndrome or symptom a substance causes in the toxic dose, you can use specially prepared nano-sized doses of that substance to treat the syndrome that it causes.
The logic of that [is that] your body does whatever it can to survive. Your symptoms are not the result of breakdown. Your symptoms are the result of that doctor inside of you that is trying to defend you and is trying to heal you. Your symptoms are part of your defenses.
And the very word, 'symptom' means sign or signal, and symptoms are just that. They're signaling us that something's wrong. Instead of turning off that signal, in homeopathy, you turn into the skid.
One of the things that your driver's education teacher probably taught you is that when you skid, you turn into t...
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Saturday, 22 July
21:15
The Global Fertility Industry Seeks To Erase Women From Procreation One Manufactured Egg At A Time "IndyWatch Feed Nthamerica"
As
scientists ramp up their fantasies about fabricated female gametes,
concerns about technology outpacing our humanity should be
high.
11:24
Can Iron Deficiency Cause Low Milk Supply? Renee Kam IBCLC BellyBelly
Have you been diagnosed with iron deficiency recently?
Are you breastfeeding and concerned iron deficiency can cause low milk supply?
Women who are breastfeeding are more likely to have low iron after birth.
This due to depletion during pregnancy and childbirth.
Can lron Deficiency Cause Low Milk Supply?
After birth, vaginal bleeding for six weeks can also leave new mothers lower in iron.
This is a vulnerable time as you establish breastfeeding and your milk supply settles.
Its common for there to be a few challenges along the way as you and your baby become skilled at breastfeeding.
Worrying about iron deficiency affecting your milk supply the last thing you need to worry about.
What Is Iron Deficiency?
Iron deficiency can occur naturally due to increased blood volume during pregnancy.
However, there is also a greater demand for iron during pregnancy.
From both the growing baby and the placenta.
During birth, its also common to lose some blood which further reduces available iron.
This leads to abnormally low levels of red blood cells or haemoglobin. This means your blood isnt able to carry as much oxygen to your muscles and tissues.
Symptoms of iron deficiency include:
- Dizziness
- Weakness
- Fatigue
- Headaches
- Shortness of breath
- Feeling cold
If low iron levels arent corrected, this can lead to anaemia.
Iron deficiency anemia is a much more severe form of iron deficiency.
You can be mildly, moderately or severely iron deficient. Iron deficiency anaemia is a more severe form of iron deficiency. This can also be mild, moderate or severe.
Iron deficiency is the most common cause of anaemia in pregnancy.
You can read more in Anaemia During Pregnancy | Causes, Symptoms and Treatment.
Iron-deficiency anaemia during pregnancy occurs in around 20% of women in developed countries.
So, can iron-deficiency anaemia be a problem for milk supply?
Iron Deficiency Anaemia May Impact Milk Supply
It is currently not clear whether iron deficiency anaemia may affect milk supply.
There is only a small amount of observational evidence available for us to look at.
These small studies suggest anaemia may be responsible for low milk supply and the cessation of breastfeeding.
However there is a link between low iron and immune function, which can...
05:49
Induction of reproductive injury by bisphenol A and the protective effects of cyanidin-3-O-glucoside and protocatechuic acid. "IndyWatch Feed Health"
PMID: Sci Total Environ. 2023 Jul 20 ;883:163615. Epub 2023 Apr 25. PMID: 37105472 Abstract Title: Induction of reproductive injury by bisphenol A and the protective effects of cyanidin-3-O-glucoside and protocatechuic acid in rats. Abstract: Bisphenol A (BPA) has attracted growing attention as a well-known environmental pollutant due to its high risk of male reproductive toxicity. In this study, transcriptomics profiling combined with metabolomic techniques was applied to explore the intervention effects of BPA-induced male reproductive toxicity. We demonstrated that cyanidin-3-O-glucoside (C3G) and its main metabolite protocatechuic acid (PCA) significantly increased testosterone and luteinizing hormone (LH) levels in the serum of rats, and improved sperm quality. Furthermore, we identified and screened differentially expressed genes (DEGs) and metabolites (DMs) that functionally enriched in the steroidogenesis-related pathways. Next, the validated results found that C3G and PCA significantly up-regulated the gene expressions of Star, Cyp11a1, Cyp17a1, Cyp19a1, Cyp7a1, Hsd3b1, Hsd3b2, Hsd17b3, Scrab1, and Ass1 in testicular. In Leydig cells, C3G and PCA dramatically alleviated apoptosis, ROS accumulation, and cell cycle arrest caused by BPA. In addition, molecular docking and simulation results implied that C3G and PCA competitively with BPA bind to the estrogen receptorsand(ERand ER) and shared common key amino acids. The main interaction modes between small molecules and estrogen receptors included-stacking, salt bridges, hydrogen bonds, and hydrophobic interactions. Therefore, our study sheds light on C3G and PCA supplementation can protect male reproduction from BPA-induced injury.
05:36
Low dose prenatal bisphenol A exposure on adiposity in male and female ICR offspring. "IndyWatch Feed Health"
PMID: Ecotoxicol Environ Saf. 2023 Jun 1 ;257:114946. Epub 2023 Apr 25. PMID: 37105096 Abstract Title: In vivo effects of low dose prenatal bisphenol A exposure on adiposity in male and female ICR offspring. Abstract: BACKGROUND: Bisphenol A (BPA) is known to exhibit endocrine disrupting activities and is associated with adiposity. We examined the obesogenic effect of prenatal BPA exposure in the present study.METHODS: Pregnant ICR mice were exposed to vehicle or BPA via the drinking water at a dose of 0.5 g/kgd throughout the gestation. Obesity-related indexes were investigated in the 12-wk-old offspring. Primary mouse embryonic fibroblasts (MEFs) collected from treated embryos were used to test effects of BPA on adipocyte differentiation.RESULTS: Offspring presented a significantly higher rate of weight gain than the control, with impaired insulin sensitivity and increased adipocyte size. Differentiation of MEFs from BPA-treated mice showed a higher propensity for the adipocyte commitment as well as up-regulation of genes enriched in lipid biosynthesis. TGF-signaling pathway was found to modulate obesogenic effect of BPA in MEF model, but estrogen signaling pathway had no effect.CONCLUSIONS: The present study provides strong evidence of the association between prenatal exposure to low dose of BPA and a significant increase in body weight in the offspring mice with a critical role played by TGF-signaling pathway. The potential interactions modulating the binding of BPA and TGF-that activate its obesogenic effects need to be examined.
Friday, 21 July
09:19
Resveratrol reliefs DEHP-induced defects during human decidualization. "IndyWatch Feed Health"
PMID: Ecotoxicol Environ Saf. 2023 Jun 15 ;258:114931. Epub 2023 Apr 28. PMID: 37121080 Abstract Title: Resveratrol reliefs DEHP-induced defects during human decidualization. Abstract: Di-(2-Ethylhexyl) phthalate (DEHP) is widely used as an additive in many plastic products. Studies have revealed that DEHP persistent exposure can affect embryonic development and lead to adverse female reproductive disorders. The establishment of pregnancy involves extensive changes in the endometrial tissue, including massive extracellular matrix (ECM) remodeling. Decidualization of the endometrium provides a suitable environment for subsequent growth by causing changes in the morphology of the uterine stromal cells, is a key process in human pregnancy. Resveratrol (RSV) is a natural polyphenolic plant antitoxin with a wide range of pharmacological effects. Growing evidence indicates that RSV has therapeutic effects on certain female reproductive disorders. In this study, the effect of DEHP on cell viability was investigated by cell proliferation assay. Cell decidualization was induced in vitro, and the downregulation of molecules associated with decidualization was confirmed through quantitative real-time PCR and western blot analysis. Immunofluorescence analysis revealed alteration in cell morphology, and found that administration of DEHP sufficiently induced ERentry into the nucleus. The effect of DEHP on cells was fully verified by RNA-seq analysis. Interestingly, an upregulation of decidual molecules was observed after rescue with RSV, which was confirmed by RNA-seq transcriptome analysis and quantitative real-time PCR assay. Additionally, the expression of ECM remodeling-related genes was significantly restored by RSV administration. The study revealed the potential mechanisms of DEHP-induced decidualization defects and the functional relieving roles of RSV while providing a perspective therapeutic candidate for alleviating the DEHP-induced deficiencies in decidualization.
05:59
Effect of Tinospora cordifolia on gestational diabetes mellitus and its complications. "IndyWatch Feed Health"
PMID: Women Health. 2023 ;63(5):359-369. Epub 2023 Apr 20. PMID: 37080903 Abstract Title: Effect ofon gestational diabetes mellitus and its complications. Abstract: Ayurvedic system of medicine uses giloy or guduchi, also known as(TC), to treat diabetes and related diseases like hyperglycemia and hyperlipididemia. However, its usage in gestational diabetes mellitus (GDM) is not well studied. The primary objective of the study was to examine the effects of water extract of TC called satva, essential oil, and hydroalcoholic (HA) extract on GDM and its complications and to explore their mechanism of action using mice model. We used streptozotocin-induced diabetes in pregnant mice as murine model and tested TC preparations for anti-GDM activities. Blood glucose, insulin, litter size, and placental weight were assessed. ELISA method was used to measure plasma insulin level to compute homeostatic model assessment of insulin resistance (HOMA-IR), quantitative insulin sensitivity check index (QUICKI), and homeostatic model assessment for assessing beta cell function (HOMA-Beta) levels to estimate insulin resistance, insulin sensitivity, and beta cell function respectively. TC-treated groups had significantly higher serum insulin levels, QUICKI, average litter size, and lower placental weight (