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Tuesday, 25 July

17:00

What Disaster Happened? 2200, The World Only Has 250 Million People "IndyWatch Feed World"

folks are finally beginning to work out the real world consequenses of a low population growth, or put more correctly the real world consequenses of actual contraction. I have been posting about this even when the only commentary was about the population explosion.

Public consciousness has yet to hit the emergency button and that may well not happen if Japan is any example. governments, if they wish to survive now have to impliment a completely new protocol.

It is my thought that we need from 18 to 24, mandatory production of four births, but not necessarily mandatory motherhood as this needs to be natural community supported at least. This obviously overrides a whole bunch of custom and custom can be partially integrated but we will see new custom also established while this whole is properly financed as well. Again it is best done through the natural community build.

Again it will be mandatory, just like the military draft and for the same reason. Male draft also needs to be concurrent in order to fitness and skill levels. I grew up on a nineteenth century farm and learned rough carpentry, safe electrical wiring, and basic plumbing and things like welding and metal working were not out of reach. my point is that all of this could have been better taught to make me proficient.

women will also want to do most of this. My only issue is that four pregnacies will mean non rigid timing.

The military does all of this in a cycle of basic training, perhaps a redo, and then core traing to bring skills up.

There will still be the academic stream, but we need to up our game there with far better tuning. most folks need to come out the shoot with ample physical skills as well as academic skills and how about actual mastery? A b is good enough, but teaching the material makes that an A. That is the...

06:58

Maternal supplementation with human milk-derived Lactiplantibacillus plantarum WLPL04 affects the immunity and gut microbiota of offspring rats. "IndyWatch Feed Health"

PMID: Food Funct. 2023 Jun 6 ;14(11):5326-5341. Epub 2023 Jun 6. PMID: 37204244 Abstract Title: Maternal supplementation with human milk-derivedWLPL04 affects the immunity and gut microbiota of offspring rats. Abstract: Pregnancy and lactation are a window period during which interventions on mothers bring beneficial effects to newborns. This study aims to investigate the effects of maternal supplementation with human-milk-derivedWLPL04-36e during pregnancy and lactation on the physiology, immunity and gut microbiota of dams and their offspring. We found that after maternal supplementation,WLPL04-36e could be detected in the intestines and extraintestinal tissues (liver, spleen, kidneys, mammary gland, MLN and brain) of dams, as well as in the intestines of their offspring. Maternal supplementation withWLPL04-36e could significantly increase the body weights of dams and their offspring during the middle to late lactation period, elevate the serum levels of IL-4, IL-6, and IL-10 of dams and IL-6 level of offspring, and increase the proportion of spleen CD4+ T lymphocytes of the offspring. Moreover,WLPL04-36e supplementation could increase the alpha diversity of milk microbiota during early and middle lactation periods, and elevated the abundance ofin the intestines of offspring at week 2 and week 3 after birth. These results suggest that maternal supplementation with human-milk-derivedcan regulate the immunity and intestinal microbiota composition of offspring and play positive roles in the growth of offspring.

Monday, 24 July

12:38

Marginal zinc deficiency alters the heart proteome of rats. "IndyWatch Feed Health"

PMID: Food Funct. 2023 May 11 ;14(9):4117-4128. Epub 2023 May 11. PMID: 37039861 Abstract Title: Marginal zinc deficiency alters the heart proteome of rats. Abstract: Zinc deficiency is closely related to cardiovascular diseases (CVDs), but the effects of marginal zinc deficiency (MZD) after birth on the heart are unknown. In this study, 4-week-old male rats were fed a low zinc diet (10 mg kg, 1/3 recommended nutrient intake, RNI) for 8 weeks. Echocardiography and histopathology were performed to assess the functional and morphological alterations of the heart. High-throughput proteomics was used to study the effects of MZD on cardiac protein expression. We found that MZD reduced food intake, body weight, serum zinc, and heart weight; however, the coefficient, zinc concentration, function, and histopathology of the heart were not changed. The heart proteome was altered in the marginal zinc-deficient diet group (MZG), compared with the normal zinc diet group (NZG). A total of 310 differentially expressed proteins (